Implication of Lipids in Calcified Aortic Valve Pathogenesis: Why Did Statins Fail?

Implication of Lipids in Calcified Aortic Valve Pathogenesis: Why Did Statins Fail?

Calcific Aortic Valve Disease (CAVD) is a fibrocalcific disease. Lipoproteins and oxidized phospholipids play a substantial role in CAVD; the level of Lp(a) has been shown to accelerate the progression of valve calcification. Indeed, oxidized phospholipids carried by Lp(a) into the aortic valve stim...

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Bibliographic Details
Main Authors: Mohamed J. Nsaibia, Anichavezhi Devendran, Eshak Goubaa, Jamal Bouitbir, Romain Capoulade, Rihab Bouchareb
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Journal of Clinical Medicine
Subjects:
aortic valve
lipids
statins
Lp(a)
PCSK9
Online Access:https://www.mdpi.com/2077-0383/11/12/3331

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