Unbiased proteomic and forward genetic screens reveal that mechanosensitive ion channel MSL10 functions at ER–plasma membrane contact sites in Arabidopsis thaliana

Unbiased proteomic and forward genetic screens reveal that mechanosensitive ion channel MSL10 functions at ER–plasma membrane contact sites in Arabidopsis thaliana

Mechanosensitive (MS) ion channels are an evolutionarily conserved way for cells to sense mechanical forces and transduce them into ionic signals. The channel properties of Arabidopsis thaliana MscS-Like (MSL)10 have been well studied, but how MSL10 signals remains largely unknown. To uncover signal...

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Bibliographic Details
Main Authors: Jennette M Codjoe, Ryan A Richardson, Fionn McLoughlin, Richard David Vierstra, Elizabeth S Haswell
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-10-01
Series:eLife
Subjects:
membrane contact sites
mechanotransduction
mechanosensitive ion channel
synaptotagmins
VAMP-associated proteins
Online Access:https://elifesciences.org/articles/80501

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