The Ophthalmic Manifestations of Down Syndrome
Down Syndrome is one of the most common chromosomal conditions in the world, affecting an estimated 1:400–1:500 births. It is a multisystem genetic disorder but has a wide range of ophthalmic findings. These include strabismus, amblyopia, accommodation defects, refractive error, eyelid abnormalities...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Children |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9067/10/2/341 |
| _version_ | 1797621663338070016 |
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| author | Emily Sun Courtney L. Kraus |
| author_facet | Emily Sun Courtney L. Kraus |
| author_sort | Emily Sun |
| collection | DOAJ |
| description | Down Syndrome is one of the most common chromosomal conditions in the world, affecting an estimated 1:400–1:500 births. It is a multisystem genetic disorder but has a wide range of ophthalmic findings. These include strabismus, amblyopia, accommodation defects, refractive error, eyelid abnormalities, nasolacrimal duct obstruction, nystagmus, keratoconus, cataracts, retinal abnormalities, optic nerve abnormalities, and glaucoma. These ophthalmic conditions are more prevalent in children with Down Syndrome than the general pediatric population, and without exception, early identification with thoughtful screening in this patient population can drastically improve prognosis and/or quality of life. |
| first_indexed | 2024-03-11T09:00:06Z |
| format | Article |
| id | doaj.art-9097a17f3314469c8d65976964d2aa4f |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-11T09:00:06Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-9097a17f3314469c8d65976964d2aa4f2023-11-16T19:49:24ZengMDPI AGChildren2227-90672023-02-0110234110.3390/children10020341The Ophthalmic Manifestations of Down SyndromeEmily Sun0Courtney L. Kraus1Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21218, USAWilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21218, USADown Syndrome is one of the most common chromosomal conditions in the world, affecting an estimated 1:400–1:500 births. It is a multisystem genetic disorder but has a wide range of ophthalmic findings. These include strabismus, amblyopia, accommodation defects, refractive error, eyelid abnormalities, nasolacrimal duct obstruction, nystagmus, keratoconus, cataracts, retinal abnormalities, optic nerve abnormalities, and glaucoma. These ophthalmic conditions are more prevalent in children with Down Syndrome than the general pediatric population, and without exception, early identification with thoughtful screening in this patient population can drastically improve prognosis and/or quality of life.https://www.mdpi.com/2227-9067/10/2/341Down SyndromeTrisomy 21strabismusamblyopianasolacrimal duct obstruction |
| spellingShingle | Emily Sun Courtney L. Kraus The Ophthalmic Manifestations of Down Syndrome Children Down Syndrome Trisomy 21 strabismus amblyopia nasolacrimal duct obstruction |
| title | The Ophthalmic Manifestations of Down Syndrome |
| title_full | The Ophthalmic Manifestations of Down Syndrome |
| title_fullStr | The Ophthalmic Manifestations of Down Syndrome |
| title_full_unstemmed | The Ophthalmic Manifestations of Down Syndrome |
| title_short | The Ophthalmic Manifestations of Down Syndrome |
| title_sort | ophthalmic manifestations of down syndrome |
| topic | Down Syndrome Trisomy 21 strabismus amblyopia nasolacrimal duct obstruction |
| url | https://www.mdpi.com/2227-9067/10/2/341 |
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