Herba Epimedii: Anti-Oxidative Properties and Its Medical Implications

Herba Epimedii is a Chinese herbal medicine with proven efficacy in treating cardiovascular diseases and osteoporosis, and in improving sexual and neurological functions. This efficacy is found to be related to the potent anti-oxidative ability of Herba Epimedii and its flavonoid components, with ic...

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Main Authors: Ho Pan Cheung, Tzi Bun Ng, Chris Lok Yin Cheng, Stephen Cho Wing Sze, Yao Tong
Format: Article
Language:English
Published: MDPI AG 2010-11-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/15/11/7861/
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author Ho Pan Cheung
Tzi Bun Ng
Chris Lok Yin Cheng
Stephen Cho Wing Sze
Yao Tong
author_facet Ho Pan Cheung
Tzi Bun Ng
Chris Lok Yin Cheng
Stephen Cho Wing Sze
Yao Tong
author_sort Ho Pan Cheung
collection DOAJ
description Herba Epimedii is a Chinese herbal medicine with proven efficacy in treating cardiovascular diseases and osteoporosis, and in improving sexual and neurological functions. This efficacy is found to be related to the potent anti-oxidative ability of Herba Epimedii and its flavonoid components, with icarrin as the main effective constituent, along with polysaccharides and vitamin C. These ingredients have been proven to be effective against oxidative-stress related pathologies (cardiovascular diseases, Alzheimer’s disease and inflammation) in animal rodent models and in vitro studies. Their anti-oxidative properties are found to be related to an inductive effect on endogenous free-radical scavenging enzymes such as catalase and glutathione peroxidase and the inherent electron-donating ability of flavonoids.
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spelling doaj.art-909d7f0a43674345b164e86e322942972022-12-22T03:28:30ZengMDPI AGMolecules1420-30492010-11-0115117861787010.3390/molecules15117861Herba Epimedii: Anti-Oxidative Properties and Its Medical ImplicationsHo Pan CheungTzi Bun NgChris Lok Yin ChengStephen Cho Wing SzeYao TongHerba Epimedii is a Chinese herbal medicine with proven efficacy in treating cardiovascular diseases and osteoporosis, and in improving sexual and neurological functions. This efficacy is found to be related to the potent anti-oxidative ability of Herba Epimedii and its flavonoid components, with icarrin as the main effective constituent, along with polysaccharides and vitamin C. These ingredients have been proven to be effective against oxidative-stress related pathologies (cardiovascular diseases, Alzheimer’s disease and inflammation) in animal rodent models and in vitro studies. Their anti-oxidative properties are found to be related to an inductive effect on endogenous free-radical scavenging enzymes such as catalase and glutathione peroxidase and the inherent electron-donating ability of flavonoids.http://www.mdpi.com/1420-3049/15/11/7861/Herba Epimediiicarrinanti-oxidantflavonoidspolysaccharidesvitamin C
spellingShingle Ho Pan Cheung
Tzi Bun Ng
Chris Lok Yin Cheng
Stephen Cho Wing Sze
Yao Tong
Herba Epimedii: Anti-Oxidative Properties and Its Medical Implications
Molecules
Herba Epimedii
icarrin
anti-oxidant
flavonoids
polysaccharides
vitamin C
title Herba Epimedii: Anti-Oxidative Properties and Its Medical Implications
title_full Herba Epimedii: Anti-Oxidative Properties and Its Medical Implications
title_fullStr Herba Epimedii: Anti-Oxidative Properties and Its Medical Implications
title_full_unstemmed Herba Epimedii: Anti-Oxidative Properties and Its Medical Implications
title_short Herba Epimedii: Anti-Oxidative Properties and Its Medical Implications
title_sort herba epimedii anti oxidative properties and its medical implications
topic Herba Epimedii
icarrin
anti-oxidant
flavonoids
polysaccharides
vitamin C
url http://www.mdpi.com/1420-3049/15/11/7861/
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AT stephenchowingsze herbaepimediiantioxidativepropertiesanditsmedicalimplications
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