Special Chimeric Antigen Receptor (CAR) Modifications of T Cells: A Review

Chimeric antigen receptor (CAR) -T cell therapy has become one of the hot topics in tumor immunity research in recent years. Although CAR-T cell therapy is highly effective in treating hematological malignancies, there are numerous obstacles that prevent CAR-T cells from having anti-tumor effects. T...

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Bibliographic Details
Main Authors: Lele Miao, Juan Zhang, Binjie Huang, Zhengchao Zhang, Song Wang, Futian Tang, Muzhou Teng, Yumin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.832765/full