Leishmanicidal activity and cytotoxicity of compounds from two Annonacea species cultivated in Northeastern Brazil

Leishmanicidal activity and cytotoxicity of compounds from two Annonacea species cultivated in Northeastern Brazil

INTRODUCTION: Visceral leishmaniasis is endemic in 88 countries, with a total of 12 million people infected and 350 million at risk. In the search for new leishmanicidal agents, alkaloids and acetogenins isolated from leaves of Annona squamosa and seeds of Annona muricata were tested against promast...

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Main Authors: Nadja Soares Vila-Nova, Selen Maia de Morais, Maria José Cajazeiras Falcão, Lyeghyna Karla Andrade Machado, Cláudia Maria Leal Beviláqua, Igor Rafael Sousa Costa, Nilce Viana Gramosa Pompeu de Sousa Brasil, Heitor Franco de Andrade Júnior
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2011-10-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Leishmaniose
Alcaloide benzilisoquinolinico
Acetogenina
Annona squamosa
Annona muricata
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000500007&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000500007&lng=en&tlng=en

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