CRP-Like Transcriptional Regulator MrpC Curbs c-di-GMP and 3′,3′-cGAMP Nucleotide Levels during Development in Myxococcus xanthus

CRP-Like Transcriptional Regulator MrpC Curbs c-di-GMP and 3′,3′-cGAMP Nucleotide Levels during Development in Myxococcus xanthus

ABSTRACT Myxococcus xanthus has a nutrient-regulated biphasic life cycle forming predatory swarms in the presence of nutrients and spore-filled fruiting bodies in the absence of nutrients. The second messenger 3′-5′, 3′-5 cyclic di-GMP (c-di-GMP) is essential during both stages of the life cycle; ho...

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Bibliographic Details
Main Authors: Sofya Kuzmich, Patrick Blumenkamp, Doreen Meier, Dobromir Szadkowski, Alexander Goesmann, Anke Becker, Lotte Søgaard-Andersen
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:mBio
Subjects:
c-di-GMP
cGAMP
CRP
Cappable-seq
sporulation
fruiting body formation
Online Access:https://journals.asm.org/doi/10.1128/mbio.00044-22

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