Perturbation of parentally biased gene expression during interspecific hybridization.
Interspecific hybridization often induces epigenetic remodeling that leads to transposon activation, gene expression changes, and loss of imprinting. These genomic changes can be deleterious and contribute to postzygotic hybrid incompatibility. In Arabidopsis, loss of genomic imprinting of PHERES1 a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0117293&type=printable |
| _version_ | 1826586608192716800 |
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| author | Diana Burkart-Waco Kathie Ngo Meric Lieberman Luca Comai |
| author_facet | Diana Burkart-Waco Kathie Ngo Meric Lieberman Luca Comai |
| author_sort | Diana Burkart-Waco |
| collection | DOAJ |
| description | Interspecific hybridization often induces epigenetic remodeling that leads to transposon activation, gene expression changes, and loss of imprinting. These genomic changes can be deleterious and contribute to postzygotic hybrid incompatibility. In Arabidopsis, loss of genomic imprinting of PHERES1 and presumed failure of Polycomb Repressive Complex contributes to seed inviability observed in A. thaliana X A. arenosa interspecific hybrids. We used this species pair to further analyze the relationship between parentally biased gene expression and postzygotic hybrid incompatibility using two A. thaliana accessions, Col-0 and C24, with differential seed survival. We found that parentally biased expression was perturbed to a similar degree in both A. thaliana hybrids for PHERES1, HDG3, and six other normally paternally expressed genes. We propose that early genome remodeling and loss of imprinting of seed development genes induces lethality in both compatible and incompatible hybrids. |
| first_indexed | 2024-12-14T16:03:33Z |
| format | Article |
| id | doaj.art-90b2835bbfed4313b75bb1952d80686d |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2025-03-14T16:12:14Z |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-90b2835bbfed4313b75bb1952d80686d2025-02-23T05:32:03ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01102e011729310.1371/journal.pone.0117293Perturbation of parentally biased gene expression during interspecific hybridization.Diana Burkart-WacoKathie NgoMeric LiebermanLuca ComaiInterspecific hybridization often induces epigenetic remodeling that leads to transposon activation, gene expression changes, and loss of imprinting. These genomic changes can be deleterious and contribute to postzygotic hybrid incompatibility. In Arabidopsis, loss of genomic imprinting of PHERES1 and presumed failure of Polycomb Repressive Complex contributes to seed inviability observed in A. thaliana X A. arenosa interspecific hybrids. We used this species pair to further analyze the relationship between parentally biased gene expression and postzygotic hybrid incompatibility using two A. thaliana accessions, Col-0 and C24, with differential seed survival. We found that parentally biased expression was perturbed to a similar degree in both A. thaliana hybrids for PHERES1, HDG3, and six other normally paternally expressed genes. We propose that early genome remodeling and loss of imprinting of seed development genes induces lethality in both compatible and incompatible hybrids.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0117293&type=printable |
| spellingShingle | Diana Burkart-Waco Kathie Ngo Meric Lieberman Luca Comai Perturbation of parentally biased gene expression during interspecific hybridization. PLoS ONE |
| title | Perturbation of parentally biased gene expression during interspecific hybridization. |
| title_full | Perturbation of parentally biased gene expression during interspecific hybridization. |
| title_fullStr | Perturbation of parentally biased gene expression during interspecific hybridization. |
| title_full_unstemmed | Perturbation of parentally biased gene expression during interspecific hybridization. |
| title_short | Perturbation of parentally biased gene expression during interspecific hybridization. |
| title_sort | perturbation of parentally biased gene expression during interspecific hybridization |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0117293&type=printable |
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