A new method for the synthesis of 4-aminobenzoic acid – an intermediate for the production of procaine

A new method for the synthesis of 4-aminobenzoic acid – an intermediate for the production of procaine

Procaine is one of the oldest local anesthetics used in medicine. When absorbed and entering the systemic circulation reduces the excitability of peripheral cholinoreactive systems. Has a blocking effect on the autonomic ganglia, reduces smooth muscle spasms, and reduces the excitability of the myoc...

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Bibliographic Details
Main Authors: A. H. Halstian, O. P. Baula, H. V. Tarasenko
Format: Article
Language:English
Published: Zaporozhye State Medical University 2022-08-01
Series:Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
Subjects:
oxidation
4-nitrotoluene
ozone
4-nitrobenzoic acid
accelerator
cobalt (ii) acetate
potassium bromide
Online Access:http://pharmed.zsmu.edu.ua/article/view/259850/258726

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