A case report of recurrent hypokalaemic periodic paralysis in a young male patient

A 21-year-old normotensive male patient presented with acute-onset flaccid paralysis with the history of a similar episode a few months back. Clinical and laboratory evaluation revealed lower motor neuron type of flaccid quadriparesis with hypokalaemia, normal anion gap metabolic acidosis, bicarbona...

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Main Authors: Pulin Gupta, Vikas T Talreja, M S Dhananjaya, Sakshi Mittal
Format: Article
Language:English
Published: SpringerOpen 2015-01-01
Series:The Egyptian Journal of Internal Medicine
Subjects:
Online Access:http://www.esim.eg.net/article.asp?issn=1110-7782;year=2015;volume=27;issue=2;spage=72;epage=74;aulast=Gupta
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author Pulin Gupta
Vikas T Talreja
M S Dhananjaya
Sakshi Mittal
author_facet Pulin Gupta
Vikas T Talreja
M S Dhananjaya
Sakshi Mittal
author_sort Pulin Gupta
collection DOAJ
description A 21-year-old normotensive male patient presented with acute-onset flaccid paralysis with the history of a similar episode a few months back. Clinical and laboratory evaluation revealed lower motor neuron type of flaccid quadriparesis with hypokalaemia, normal anion gap metabolic acidosis, bicarbonaturia and transtubular potassium concentration gradient more than 7. Subsequently, urine acidification test (by ammonium chloride challenge test) was performed and diagnosis of renal tubular acidosis was established. The patient ultrasound did not show nephrocalcinosis, and history of recurrent diarrhoea preceding the attack revealed that the patient also had coeliac disease. The patient responded to conservative management (Sohl′s solution) and gluten-free diet.
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spelling doaj.art-90b5febd44bc4abda20b1dbb88b6d03b2022-12-21T23:10:04ZengSpringerOpenThe Egyptian Journal of Internal Medicine1110-77822090-90982015-01-01272727410.4103/1110-7782.158001A case report of recurrent hypokalaemic periodic paralysis in a young male patientPulin GuptaVikas T TalrejaM S DhananjayaSakshi MittalA 21-year-old normotensive male patient presented with acute-onset flaccid paralysis with the history of a similar episode a few months back. Clinical and laboratory evaluation revealed lower motor neuron type of flaccid quadriparesis with hypokalaemia, normal anion gap metabolic acidosis, bicarbonaturia and transtubular potassium concentration gradient more than 7. Subsequently, urine acidification test (by ammonium chloride challenge test) was performed and diagnosis of renal tubular acidosis was established. The patient ultrasound did not show nephrocalcinosis, and history of recurrent diarrhoea preceding the attack revealed that the patient also had coeliac disease. The patient responded to conservative management (Sohl′s solution) and gluten-free diet.http://www.esim.eg.net/article.asp?issn=1110-7782;year=2015;volume=27;issue=2;spage=72;epage=74;aulast=GuptaAmmonium chloride challenge test, distal renal tubular acidosis, hypokalaemic periodic paralysis, Sohl′s solution
spellingShingle Pulin Gupta
Vikas T Talreja
M S Dhananjaya
Sakshi Mittal
A case report of recurrent hypokalaemic periodic paralysis in a young male patient
The Egyptian Journal of Internal Medicine
Ammonium chloride challenge test, distal renal tubular acidosis, hypokalaemic periodic paralysis, Sohl′s solution
title A case report of recurrent hypokalaemic periodic paralysis in a young male patient
title_full A case report of recurrent hypokalaemic periodic paralysis in a young male patient
title_fullStr A case report of recurrent hypokalaemic periodic paralysis in a young male patient
title_full_unstemmed A case report of recurrent hypokalaemic periodic paralysis in a young male patient
title_short A case report of recurrent hypokalaemic periodic paralysis in a young male patient
title_sort case report of recurrent hypokalaemic periodic paralysis in a young male patient
topic Ammonium chloride challenge test, distal renal tubular acidosis, hypokalaemic periodic paralysis, Sohl′s solution
url http://www.esim.eg.net/article.asp?issn=1110-7782;year=2015;volume=27;issue=2;spage=72;epage=74;aulast=Gupta
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