| Summary: | Background: There is a lot of discussion on bariatric surgery and its effect on weight loss as well as resolution of associated conditions such as diabetes, sleep apnea, and thyroid imbalance. Recent reports also indicate role of laparoscopic sleeve gastrectomy (LSG) in non-obese diabetics. Aims: This study was undertaken to assess medium-term effects of LSG on body weight and co-morbid factors such as diabetes, hypertension, and thyroid imbalance. Materials and Methods: A total of 42 obese subjects (19 males and 23 females; age: 23-65 years; body mass index [BMI]: 45 ± 5 kg/m¼) underwent evaluation of anthropometric/clinical parameters and blood sugar, hypertension and thyroid function tests before, 3 and 9-15 months after LSG. Results: Mean BMI decreased from 45 to 38 after 3 months and 30 at 9-15 months after surgery. Remission of type 2 diabetes mellitus and hypertension occurred in all patients except one. Sleep apnea and asthma was cured in all five patients. Out of the five patients with thyroid imbalance, all except one were off medication within 5 months. Conclusion: Our study showed that LSG is effective in producing a significant and sustained weight loss and improving diabetes mellitus, hypertension, and other co-morbid factors in obese patients.
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