CRISPRi-Mediated Down-Regulation of the Cinnamate-4-Hydroxylase (C4H) Gene Enhances the Flavonoid Biosynthesis in <i>Nicotiana tabacum</i>

CRISPRi-Mediated Down-Regulation of the Cinnamate-4-Hydroxylase (C4H) Gene Enhances the Flavonoid Biosynthesis in <i>Nicotiana tabacum</i>

Flavonoids are an important class of natural compounds present in plants. However, despite various known biological activities and therapeutic potential, the low abundance of flavonoids in nature limits their development for industrial applications. In this study, we aimed to enhance flavonoid produ...

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Bibliographic Details
Main Authors:	Chou Khai Soong Karlson, Siti Nurfadhlina Mohd Noor, Norzulaani Khalid, Boon Chin Tan
Format:	Article
Language:	English
Published:	MDPI AG 2022-07-01
Series:	Biology
Subjects:	metabolic engineering cell suspension culture CRISPRi flavonoids gene silencing
Online Access:	https://www.mdpi.com/2079-7737/11/8/1127

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