Alteration of heart rate variability in patients with Parkinson's disease after subthalamic nucleus deep brain stimulation: a Meta-analysis
Objective To evaluate the changes of heart rate variability (HRV) after subthalamic nucleus deep brain stimulation (STN-DBS) in patients with Parkinson's disease (PD). Methods Retrieve relevant cohort studies from online databases (January 1, 2000-December 1, 2017) in PubMed, EMBASE/SCOPUS, Coc...
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| Format: | Article |
| Language: | English |
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Tianjin Huanhu Hospital
2018-08-01
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| Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
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| Online Access: | http://www.cjcnn.org/index.php/cjcnn/article/view/1824 |
| _version_ | 1818649771632492544 |
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| author | Xiao-yue LUO Ru-wei OU Hui-fang SHANG |
| author_facet | Xiao-yue LUO Ru-wei OU Hui-fang SHANG |
| author_sort | Xiao-yue LUO |
| collection | DOAJ |
| description | Objective To evaluate the changes of heart rate variability (HRV) after subthalamic nucleus deep brain stimulation (STN-DBS) in patients with Parkinson's disease (PD). Methods Retrieve relevant cohort studies from online databases (January 1, 2000-December 1, 2017) in PubMed, EMBASE/SCOPUS, Cochrane Online Library, China National Knowledge Infrastructure (CNKI), Wanfang Data and VIP database with key words: subthalamic nucleus, deep brain stimulation, DBS, STN, electrical stimulation, Parkinson disease, heart rate variability. Low-frequency power (LF), high-frequency power (HF) and LF/HF of HRV were applied as evaluation indexes. Quality of studies was evaluated by using Newcastle-Ottawa Scale (NOS). All data were pooled by RevMan 5.3 software for Meta-analysis. Results We enrolled 28 English articles, from which 6 studies with NOS score 7 were chosen after excluding duplicates and those not meeting the inclusion criteria. A total of 101 PD patients undergoing STN-DBS were included. Meta-analysis showed that there were no significant differences in the LF of HRV (SMD = 0.050, 95%CI: -0.230-0.330; P = 0.740), HF of HRV (SMD = 0.160, 95%CI: - 0.120-0.430; P = 0.270), and LF/HF of HRV (SMD = 0.110, 95%CI: -0.220-0.440; P = 0.500) in patients with PD before and after the treatment of STN-DBS. Conclusions STN-DBS does not change HRV of patients with PD. |
| first_indexed | 2024-12-17T01:39:37Z |
| format | Article |
| id | doaj.art-90bc0a4a7d71458188f78a4a50971910 |
| institution | Directory Open Access Journal |
| issn | 1672-6731 |
| language | English |
| last_indexed | 2024-12-17T01:39:37Z |
| publishDate | 2018-08-01 |
| publisher | Tianjin Huanhu Hospital |
| record_format | Article |
| series | Chinese Journal of Contemporary Neurology and Neurosurgery |
| spelling | doaj.art-90bc0a4a7d71458188f78a4a509719102022-12-21T22:08:20ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312018-08-0118860260710.3969/j.issn.1672-6731.2018.08.0081779Alteration of heart rate variability in patients with Parkinson's disease after subthalamic nucleus deep brain stimulation: a Meta-analysisXiao-yue LUO0Ru-wei OU1Hui-fang SHANG2Department of Neurology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, ChinaDepartment of Neurology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, ChinaDepartment of Neurology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, ChinaObjective To evaluate the changes of heart rate variability (HRV) after subthalamic nucleus deep brain stimulation (STN-DBS) in patients with Parkinson's disease (PD). Methods Retrieve relevant cohort studies from online databases (January 1, 2000-December 1, 2017) in PubMed, EMBASE/SCOPUS, Cochrane Online Library, China National Knowledge Infrastructure (CNKI), Wanfang Data and VIP database with key words: subthalamic nucleus, deep brain stimulation, DBS, STN, electrical stimulation, Parkinson disease, heart rate variability. Low-frequency power (LF), high-frequency power (HF) and LF/HF of HRV were applied as evaluation indexes. Quality of studies was evaluated by using Newcastle-Ottawa Scale (NOS). All data were pooled by RevMan 5.3 software for Meta-analysis. Results We enrolled 28 English articles, from which 6 studies with NOS score 7 were chosen after excluding duplicates and those not meeting the inclusion criteria. A total of 101 PD patients undergoing STN-DBS were included. Meta-analysis showed that there were no significant differences in the LF of HRV (SMD = 0.050, 95%CI: -0.230-0.330; P = 0.740), HF of HRV (SMD = 0.160, 95%CI: - 0.120-0.430; P = 0.270), and LF/HF of HRV (SMD = 0.110, 95%CI: -0.220-0.440; P = 0.500) in patients with PD before and after the treatment of STN-DBS. Conclusions STN-DBS does not change HRV of patients with PD.http://www.cjcnn.org/index.php/cjcnn/article/view/1824Parkinson diseaseDeep brain stimulationSubthalamic nucleusHeart rateMeta-analysis |
| spellingShingle | Xiao-yue LUO Ru-wei OU Hui-fang SHANG Alteration of heart rate variability in patients with Parkinson's disease after subthalamic nucleus deep brain stimulation: a Meta-analysis Chinese Journal of Contemporary Neurology and Neurosurgery Parkinson disease Deep brain stimulation Subthalamic nucleus Heart rate Meta-analysis |
| title | Alteration of heart rate variability in patients with Parkinson's disease after subthalamic nucleus deep brain stimulation: a Meta-analysis |
| title_full | Alteration of heart rate variability in patients with Parkinson's disease after subthalamic nucleus deep brain stimulation: a Meta-analysis |
| title_fullStr | Alteration of heart rate variability in patients with Parkinson's disease after subthalamic nucleus deep brain stimulation: a Meta-analysis |
| title_full_unstemmed | Alteration of heart rate variability in patients with Parkinson's disease after subthalamic nucleus deep brain stimulation: a Meta-analysis |
| title_short | Alteration of heart rate variability in patients with Parkinson's disease after subthalamic nucleus deep brain stimulation: a Meta-analysis |
| title_sort | alteration of heart rate variability in patients with parkinson s disease after subthalamic nucleus deep brain stimulation a meta analysis |
| topic | Parkinson disease Deep brain stimulation Subthalamic nucleus Heart rate Meta-analysis |
| url | http://www.cjcnn.org/index.php/cjcnn/article/view/1824 |
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