A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model
The currents of optical stimulation devices with tethered or untethered systems have various disadvantages, including optical fiber breakage, disrupted animal movements, heavy batteries carried on heads, and high-frequency electromagnetic impacts. Our novel wireless remote control was developed to a...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-10-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/20/20/5869 |
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| author | Arthur C. Tsai Andrew Chih Wei Huang Ying Hao Yu Chii-Shyang Kuo Chih-Chan Hsu Yeou San Lim Bai Chuang Shyu |
| author_facet | Arthur C. Tsai Andrew Chih Wei Huang Ying Hao Yu Chii-Shyang Kuo Chih-Chan Hsu Yeou San Lim Bai Chuang Shyu |
| author_sort | Arthur C. Tsai |
| collection | DOAJ |
| description | The currents of optical stimulation devices with tethered or untethered systems have various disadvantages, including optical fiber breakage, disrupted animal movements, heavy batteries carried on heads, and high-frequency electromagnetic impacts. Our novel wireless remote control was developed to address these issues. The novel wireless device uses a magnetic resonance technique to modify the deficits of the conventional magnetic induction or radio-frequency power sources. The present device emits a strong and steady electromagnetic power. It is cheaper than previous versions, and the receiver coil on its head is very light (≦ 1 g). For the present wireless remote-controlled device, the electromagnetic field’s range (i.e., +5 cm and −5 cm of the outside coil) is larger than the range for the magnetic induction and radio-frequency power sources. The present device controls animals’ behavior by the electromagnetic field’s effective range via photostimulation. The novel wireless remote-controlled device with a magnetic resonance technique can be applied in many behavioral tasks in mice and rats. To avoid the adverse effects of high radio frequency and to extend the electromagnetic field’s range, this novel technique serves as a helpful tool to modulate the neuronal activity of target neurons in specific brain areas for optogenetic experiments. |
| first_indexed | 2024-03-10T15:33:37Z |
| format | Article |
| id | doaj.art-90bcb12b3ad9486d949bfba1b603153c |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-10T15:33:37Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-90bcb12b3ad9486d949bfba1b603153c2023-11-20T17:26:10ZengMDPI AGSensors1424-82202020-10-012020586910.3390/s20205869A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal ModelArthur C. Tsai0Andrew Chih Wei Huang1Ying Hao Yu2Chii-Shyang Kuo3Chih-Chan Hsu4Yeou San Lim5Bai Chuang Shyu6Institute of Statistical Science, Academia Sinica, Taipei 11529, TaiwanDepartment of Psychology, Fo Guang University, Yilan County 26247, TaiwanDepartment of Psychology, Fo Guang University, Yilan County 26247, TaiwanInstitute of Statistical Science, Academia Sinica, Taipei 11529, TaiwanInstitute of Statistical Science, Academia Sinica, Taipei 11529, TaiwanDepartment of Psychology, Fo Guang University, Yilan County 26247, TaiwanInstitute of Biomedical Sciences, Academia Sinica, Taipei 1529, TaiwanThe currents of optical stimulation devices with tethered or untethered systems have various disadvantages, including optical fiber breakage, disrupted animal movements, heavy batteries carried on heads, and high-frequency electromagnetic impacts. Our novel wireless remote control was developed to address these issues. The novel wireless device uses a magnetic resonance technique to modify the deficits of the conventional magnetic induction or radio-frequency power sources. The present device emits a strong and steady electromagnetic power. It is cheaper than previous versions, and the receiver coil on its head is very light (≦ 1 g). For the present wireless remote-controlled device, the electromagnetic field’s range (i.e., +5 cm and −5 cm of the outside coil) is larger than the range for the magnetic induction and radio-frequency power sources. The present device controls animals’ behavior by the electromagnetic field’s effective range via photostimulation. The novel wireless remote-controlled device with a magnetic resonance technique can be applied in many behavioral tasks in mice and rats. To avoid the adverse effects of high radio frequency and to extend the electromagnetic field’s range, this novel technique serves as a helpful tool to modulate the neuronal activity of target neurons in specific brain areas for optogenetic experiments.https://www.mdpi.com/1424-8220/20/20/5869wireless remote-controlled devicemagnetic resonanceuntethered optical stimulationoptogeneticsratmice |
| spellingShingle | Arthur C. Tsai Andrew Chih Wei Huang Ying Hao Yu Chii-Shyang Kuo Chih-Chan Hsu Yeou San Lim Bai Chuang Shyu A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model Sensors wireless remote-controlled device magnetic resonance untethered optical stimulation optogenetics rat mice |
| title | A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model |
| title_full | A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model |
| title_fullStr | A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model |
| title_full_unstemmed | A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model |
| title_short | A Wireless Magnetic Resonance Device for Optogenetic Applications in an Animal Model |
| title_sort | wireless magnetic resonance device for optogenetic applications in an animal model |
| topic | wireless remote-controlled device magnetic resonance untethered optical stimulation optogenetics rat mice |
| url | https://www.mdpi.com/1424-8220/20/20/5869 |
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