Prognostic Significance of Programmed Cell Death Ligand 1 (PD-L1), CD8+ Tumor-Infiltrating Lymphocytes and p53 in Non-Small Cell Lung Cancer: An Immunohistochemical Study

Prognostic Significance of Programmed Cell Death Ligand 1 (PD-L1), CD8+ Tumor-Infiltrating Lymphocytes and p53 in Non-Small Cell Lung Cancer: An Immunohistochemical Study

Objective: Programmed cell death ligand-1 interacts with the immune receptors on the surface of CD8+ tumor infiltrating lymphocytes and PD-1, thereby blocking its anti-tumor activity. Therapeutics suppression of this interaction will show a promise in the treatment of non-small cell lung cancer by r...

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Bibliographic Details
Main Authors: Hayam E. RASHED, Aziza E. ABDELRAHMAN, Mohamed ABDELGAWAD, Safa BALATA, Mohamed El SHABRAWY
Format: Article
Language:English
Published: Federation of Turkish Pathology Societies 2017-09-01
Series:Türk Patoloji Dergisi
Subjects:
PD-L1
p53
Tumor infiltrating lymphocytes
Non-small cell lung cancer
Immunohistochemistry
Online Access:http://www.turkjpath.org/pdf.php3?id=1834

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