Polyphosphate degradation by Nudt3-Zn2+ mediates oxidative stress response

Polyphosphate degradation by Nudt3-Zn2+ mediates oxidative stress response

Summary: Polyphosphate (polyP) is a polymer of hundreds of phosphate residues present in all organisms. In mammals, polyP is involved in crucial physiological processes, including coagulation, inflammation, and stress response. However, after decades of research, the metabolic enzymes are still unkn...

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Bibliographic Details
Main Authors: Bàrbara Samper-Martín, Ana Sarrias, Blanca Lázaro, Marta Pérez-Montero, Rosalía Rodríguez-Rodríguez, Mariana P.C. Ribeiro, Aitor Bañón, Don Wolfgeher, Henning J. Jessen, Berta Alsina, Josep Clotet, Stephen J. Kron, Adolfo Saiardi, Javier Jiménez, Samuel Bru
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Cell Reports
Subjects:
polyphosphate
Nudt3
NUDIX
mammalian polyphosphatase
oxidative stress
DNA damage
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721014820

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http://www.sciencedirect.com/science/article/pii/S2211124721014820

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