Ubiquitin Ligases in Longevity and Aging Skeletal Muscle

Ubiquitin Ligases in Longevity and Aging Skeletal Muscle

The development and prevalence of diseases associated with aging presents a global health burden on society. One hallmark of aging is the loss of proteostasis which is caused in part by alterations to the ubiquitin–proteasome system (UPS) and lysosome–autophagy system leading to impaired function an...

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Bibliographic Details
Main Authors:	David C. Hughes, Leslie M. Baehr, David S. Waddell, Adam P. Sharples, Sue C. Bodine
Format:	Article
Language:	English
Published:	MDPI AG 2022-07-01
Series:	International Journal of Molecular Sciences
Subjects:	protein degradation proteostasis E3 ubiquitin ligase healthspan sarcopenia
Online Access:	https://www.mdpi.com/1422-0067/23/14/7602

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