Occurrence of COPD in Patients with Respiratory Allergy: A Clinico-Spirometric Evaluation in a Tertiary Hospital, Kolkata
Introduction: Smoking is established as the most important causative factor responsible for Chronic Obstructive Pulmonary Disease (COPD). Occurrence of allergy in COPD patients causes acute exacerbation of this disease, but role of allergy is not established in aetiopathogenesis of COPD. Aim: T...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2017-05-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/9841/25643_CE(RA1)_F(T)_PF1(PG_SS)_PFA(PG_SS).pdf |
| Summary: | Introduction: Smoking is established as the most important
causative factor responsible for Chronic Obstructive Pulmonary
Disease (COPD). Occurrence of allergy in COPD patients
causes acute exacerbation of this disease, but role of allergy is
not established in aetiopathogenesis of COPD.
Aim: The present study was aimed at evaluation of occurrence
of COPD in patients having symptoms suggestive of respiratory
allergy.
Materials and Methods: An observational cross-sectional study
was conducted to evaluate occurrence of COPD in patients
having respiratory allergic symptoms by routine spirometric
screening. Five hundred and fifty urban patients aged 18-60
years (both gender) ailing from chronic respiratory symptoms
like cough, wheeze and Shortness Of Breath (SOB), who were
referred from OPDs of RGKMCH, Kolkata, were included in this
study. After obtaining detailed clinical profile, patients were
divided into two groups: subjects having additional clinical
symptoms suggestive of respiratory allergy (n=260) like nasal
catarrh, nasal stuffiness and sneezing and subjects with no
symptoms suggestive of respiratory allergy (n=290). Thereafter,
routine spirometry was carried out following recommendations
of ATS/ERS (2005). Patients were then categorized based on
FVC, FEV1
, FEV1
/FVC, FEF25-75 and PEFR percent predicted
values.
Results: Study revealed that 18.97% of non-allergic population
was suffering from COPD whereas only 7.69% of allergic
subjects had COPD. This difference was statistically highly
significant (p=0.0001). Although there was no significant
difference in prevalence of respiratory symptoms between
these two groups.
Conclusion: Present study concludes that patients with
respiratory allergy may have coexistent COPD but occurrence
of COPD is much less than that in patients with no respiratory
allergy. |
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| ISSN: | 2249-782X 0973-709X |