Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility?

Pulmonary arterial hypertension (PAH) is characterized by an insult in the pulmonary vasculature, with subsequent right ventricular (RV) adaptation to the increased afterload that ultimately leads to RV failure. The awareness of the importance of RV function in PAH has increased considerably because...

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Main Authors: Ioannis T. Farmakis, Eftychia Demerouti, Panagiotis Karyofyllis, George Karatasakis, Maria Stratinaki, Dimitrios Tsiapras, George Athanassopoulos, Vassilios Voudris, George Giannakoulas
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/13/2826
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author Ioannis T. Farmakis
Eftychia Demerouti
Panagiotis Karyofyllis
George Karatasakis
Maria Stratinaki
Dimitrios Tsiapras
George Athanassopoulos
Vassilios Voudris
George Giannakoulas
author_facet Ioannis T. Farmakis
Eftychia Demerouti
Panagiotis Karyofyllis
George Karatasakis
Maria Stratinaki
Dimitrios Tsiapras
George Athanassopoulos
Vassilios Voudris
George Giannakoulas
author_sort Ioannis T. Farmakis
collection DOAJ
description Pulmonary arterial hypertension (PAH) is characterized by an insult in the pulmonary vasculature, with subsequent right ventricular (RV) adaptation to the increased afterload that ultimately leads to RV failure. The awareness of the importance of RV function in PAH has increased considerably because right heart failure is the predominant cause of death in PAH patients. Given its wide availability and reduced cost, echocardiography is of paramount importance in the evaluation of the right heart in PAH. Several echocardiographic parameters have been shown to have prognostic implications in PAH; however, the role of echocardiography in the risk assessment of the PAH patient is limited under the current guidelines. This review discusses the echocardiographic evaluation of the RV in PAH and during therapy, and its prognostic implications, as well as the potential significant role of repeated echocardiographic assessment in the follow-up of patients with PAH.
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spelling doaj.art-90c960db069a46a5937d7dd2ff34c6952023-11-22T01:53:32ZengMDPI AGJournal of Clinical Medicine2077-03832021-06-011013282610.3390/jcm10132826Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility?Ioannis T. Farmakis0Eftychia Demerouti1Panagiotis Karyofyllis2George Karatasakis3Maria Stratinaki4Dimitrios Tsiapras5George Athanassopoulos6Vassilios Voudris7George Giannakoulas8Cardiology Department, AHEPA University Hospital, Aristotle University of Thessaloniki, PC 54621 Thessaloniki, GreeceNon-Invasive Cardiology Department, Onassis Cardiac Surgery Center, PC 17674 Athens, GreeceInvasive-Cardiology Department, Onassis Cardiac Surgery Center, PC 17674 Athens, GreeceNon-Invasive Cardiology Department, Onassis Cardiac Surgery Center, PC 17674 Athens, GreeceDepartment of Cardiology, General Hospital Venizeleio, PC 71409 Irákleion, GreeceNon-Invasive Cardiology Department, Onassis Cardiac Surgery Center, PC 17674 Athens, GreeceNon-Invasive Cardiology Department, Onassis Cardiac Surgery Center, PC 17674 Athens, GreeceInvasive-Cardiology Department, Onassis Cardiac Surgery Center, PC 17674 Athens, GreeceCardiology Department, AHEPA University Hospital, Aristotle University of Thessaloniki, PC 54621 Thessaloniki, GreecePulmonary arterial hypertension (PAH) is characterized by an insult in the pulmonary vasculature, with subsequent right ventricular (RV) adaptation to the increased afterload that ultimately leads to RV failure. The awareness of the importance of RV function in PAH has increased considerably because right heart failure is the predominant cause of death in PAH patients. Given its wide availability and reduced cost, echocardiography is of paramount importance in the evaluation of the right heart in PAH. Several echocardiographic parameters have been shown to have prognostic implications in PAH; however, the role of echocardiography in the risk assessment of the PAH patient is limited under the current guidelines. This review discusses the echocardiographic evaluation of the RV in PAH and during therapy, and its prognostic implications, as well as the potential significant role of repeated echocardiographic assessment in the follow-up of patients with PAH.https://www.mdpi.com/2077-0383/10/13/2826echocardiographypulmonary arterial hypertensionright ventricle
spellingShingle Ioannis T. Farmakis
Eftychia Demerouti
Panagiotis Karyofyllis
George Karatasakis
Maria Stratinaki
Dimitrios Tsiapras
George Athanassopoulos
Vassilios Voudris
George Giannakoulas
Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility?
Journal of Clinical Medicine
echocardiography
pulmonary arterial hypertension
right ventricle
title Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility?
title_full Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility?
title_fullStr Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility?
title_full_unstemmed Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility?
title_short Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility?
title_sort echocardiography in pulmonary arterial hypertension is it time to reconsider its prognostic utility
topic echocardiography
pulmonary arterial hypertension
right ventricle
url https://www.mdpi.com/2077-0383/10/13/2826
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