Iodine and thyroid function

Severe iodine deficiency causes hypothyroidism that results in impaired somatic growth and motor development in children. Mild and moderate iodine deficiencies cause multifocal autonomous growth of thyroid, which results in thyrotoxicosis. On the other hand, iodine excess is associated with the deve...

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Main Author: Hye Rim Chung
Format: Article
Language:English
Published: Korean Society of Pediatric Endocrinology 2014-03-01
Series:Annals of Pediatric Endocrinology & Metabolism
Subjects:
Online Access:http://e-apem.org/upload/pdf/apem-19-8.pdf
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author Hye Rim Chung
author_facet Hye Rim Chung
author_sort Hye Rim Chung
collection DOAJ
description Severe iodine deficiency causes hypothyroidism that results in impaired somatic growth and motor development in children. Mild and moderate iodine deficiencies cause multifocal autonomous growth of thyroid, which results in thyrotoxicosis. On the other hand, iodine excess is associated with the development of hypothyroidism and thyroid autoimmunity. In areas of iodine deficiency, a sudden increase in iodine intake is associated with transient hyperthyroidism. Recent studies demonstrated that long-term thyroid function of subjects who experienced both iodine deficiency and iodine excess during childhood tended to be abnormal despite optimization of their current iodine intake. Iodine status in the Korean Peninsula is very unique because people in the Republic of Korea have been shown to have predominantly excessive iodine levels, whereas the Democratic People's Republic of Korea is known to be an iodine-deficient area. Further research is warranted to verify the optimal ranges of iodine intake and to clarify the effects of iodine intake on thyroid disorders in the Korean Peninsula.
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spelling doaj.art-90ca32b6fa2146d9b5e4b911734f59832022-12-22T00:20:22ZengKorean Society of Pediatric EndocrinologyAnnals of Pediatric Endocrinology & Metabolism2287-10122287-12922014-03-0119181210.6065/apem.2014.19.1.8564Iodine and thyroid functionHye Rim Chung0Department of Pediatrics, Seoul National University Bundang Hospital, Seongnam, Korea.Severe iodine deficiency causes hypothyroidism that results in impaired somatic growth and motor development in children. Mild and moderate iodine deficiencies cause multifocal autonomous growth of thyroid, which results in thyrotoxicosis. On the other hand, iodine excess is associated with the development of hypothyroidism and thyroid autoimmunity. In areas of iodine deficiency, a sudden increase in iodine intake is associated with transient hyperthyroidism. Recent studies demonstrated that long-term thyroid function of subjects who experienced both iodine deficiency and iodine excess during childhood tended to be abnormal despite optimization of their current iodine intake. Iodine status in the Korean Peninsula is very unique because people in the Republic of Korea have been shown to have predominantly excessive iodine levels, whereas the Democratic People's Republic of Korea is known to be an iodine-deficient area. Further research is warranted to verify the optimal ranges of iodine intake and to clarify the effects of iodine intake on thyroid disorders in the Korean Peninsula.http://e-apem.org/upload/pdf/apem-19-8.pdfThyroidIodineHypothyroidism
spellingShingle Hye Rim Chung
Iodine and thyroid function
Annals of Pediatric Endocrinology & Metabolism
Thyroid
Iodine
Hypothyroidism
title Iodine and thyroid function
title_full Iodine and thyroid function
title_fullStr Iodine and thyroid function
title_full_unstemmed Iodine and thyroid function
title_short Iodine and thyroid function
title_sort iodine and thyroid function
topic Thyroid
Iodine
Hypothyroidism
url http://e-apem.org/upload/pdf/apem-19-8.pdf
work_keys_str_mv AT hyerimchung iodineandthyroidfunction