αCaMKII in the lateral amygdala mediates PTSD-Like behaviors and NMDAR-Dependent LTD

αCaMKII in the lateral amygdala mediates PTSD-Like behaviors and NMDAR-Dependent LTD

Post-traumatic stress disorder (PTSD) is a psychiatric disorder that afflicts many individuals. However, its molecular and cellular mechanisms remain largely unexplored. Here, we found PTSD susceptible mice exhibited significant up-regulation of alpha-Ca2+/calmodulin-dependent kinase II (αCaMKII) in...

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Bibliographic Details
Main Authors: Shuming An, Jiayue Wang, Xuliang Zhang, Yanhong Duan, Yiqiong Xu, Junyan Lv, Dasheng Wang, Huan Zhang, Gal Richter-Levin, Oded Klavir, Buwei Yu, Xiaohua Cao
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Neurobiology of Stress
Subjects:
Posttraumatic stress disorder (PTSD)
αCaMKII
Cued fear conditioning
LTD
Anxiety
Amygdala
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289521000679

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