FBP1 /miR-24-1/enhancer axis activation blocks renal cell carcinoma progression via Warburg effect

FBP1 /miR-24-1/enhancer axis activation blocks renal cell carcinoma progression via Warburg effect

Warburg effect is a pivotal hallmark of cancers and appears prevalently in renal cell carcinoma (RCC). FBP1 plays a negative role in Warburg effect as a rate-limiting enzyme in gluconeogenesis, yet its mechanism in RCC remains to be further characterized. Herein, we revealed that FBP1 was downregula...

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Bibliographic Details
Main Authors: Dongen Ju, Ying Liang, Guangdong Hou, Wanxiang Zheng, Geng Zhang, Xinlong Dun, Di Wei, Fei Yan, Lei Zhang, Dong Lai, Jiarui Yuan, Yu Zheng, Fuli Wang, Ping Meng, Yong Wang, Wenqiang Yu, Jianlin Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
FBP1
renal cell carcinoma
enhancer
Warburg Effect
miR-24-1
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.928373/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.928373/full

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