Development of a Prognostic Five-Gene Signature for Diffuse Lower-Grade Glioma Patients

Development of a Prognostic Five-Gene Signature for Diffuse Lower-Grade Glioma Patients

Background: Diffuse lower-grade gliomas (LGGs) are infiltrative and heterogeneous neoplasms. Gene signature including multiple protein-coding genes (PCGs) is widely used as a tumor marker. This study aimed to construct a multi-PCG signature to predict survival for LGG patients.Methods: LGG data incl...

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Bibliographic Details
Main Authors: Qiang Zhang, Wenhao Liu, Shun-Bin Luo, Fu-Chen Xie, Xiao-Jun Liu, Ren-Ai Xu, Lixi Chen, Zhilin Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Neurology
Subjects:
lower-grade glioma
signature
prognostic biomarker
survival
gene expression
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.633390/full

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