Histopathological Analysis of Gastric Biopsies using Updated Sydney System
Objective: To analyse histopathological findings in gastric biopsies of patients with dyspepsia using an updated Sydney System. Study Design: Retrospective longitudinal study. Place and Duration of Study: Histopathology Department, Najran Armed Forces Hospital (NAFH), Saudi Arabia, from Jan 2...
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| Format: | Article |
| Language: | English |
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Army Medical College Rawalpindi
2022-12-01
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| Series: | Pakistan Armed Forces Medical Journal |
| Subjects: | |
| Online Access: | https://pafmj.org/index.php/PAFMJ/article/view/6458 |
| _version_ | 1828048806176882688 |
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| author | Muhammad Zubair Nabeel Khan Afridi Muhammad Amir Nawaid Hassan Tariq Akhter Ali Bajwa Naveed Khan |
| author_facet | Muhammad Zubair Nabeel Khan Afridi Muhammad Amir Nawaid Hassan Tariq Akhter Ali Bajwa Naveed Khan |
| author_sort | Muhammad Zubair |
| collection | DOAJ |
| description |
Objective: To analyse histopathological findings in gastric biopsies of patients with dyspepsia using an updated Sydney System.
Study Design: Retrospective longitudinal study.
Place and Duration of Study: Histopathology Department, Najran Armed Forces Hospital (NAFH), Saudi Arabia, from Jan 2013 to Mar 2020.
Methodology: A total of 408 cases whose gastric biopsies were included in the study, and their histological features were studied.
Results: Among 408 patients included in the study, 191(46.8%) were males, and 217(53.2%) were females. The mean age was 37.0±15.0 years. A total of 343 patients showed gastritis, which was mild 152(44.3%), moderate 158(46.1%) and severe 33(9.6%), respectively. The activity was observed in 200(49.0%) patients. H.pylori infection was observed in 196(48.0%) patients and intestinal metaplasia in 9(2.2%) patients.
Conclusion: Most of the cases with dyspepsia showed histological evidence of gastritis. However, a significant number of patients had no gastric mucosal abnormality. Therefore, adequate and timely treatment of H.pylori infection can significantly reduce related morbidity.
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| first_indexed | 2024-04-10T19:02:28Z |
| format | Article |
| id | doaj.art-90cc6272db22497eac3c9aa20d679993 |
| institution | Directory Open Access Journal |
| issn | 0030-9648 2411-8842 |
| language | English |
| last_indexed | 2024-04-10T19:02:28Z |
| publishDate | 2022-12-01 |
| publisher | Army Medical College Rawalpindi |
| record_format | Article |
| series | Pakistan Armed Forces Medical Journal |
| spelling | doaj.art-90cc6272db22497eac3c9aa20d6799932023-01-31T08:20:17ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422022-12-0172610.51253/pafmj.v72i6.6458Histopathological Analysis of Gastric Biopsies using Updated Sydney SystemMuhammad Zubair0Nabeel Khan Afridi1Muhammad Amir Nawaid2Hassan Tariq3Akhter Ali Bajwa4Naveed Khan5Najran Armed Forces Hospital, Saudi ArabiaNajran Armed Forces Hospital, Saudi ArabiaNajran Armed Forces Hospital, Saudi ArabiaArmed Forces Institute of Pathology/National University of Medical Sciences (NUMS) Rawalpindi PakistanCombined Military Hospital, Thall/National University of Medical Sciences (NUMS) PakistanCombined Military Hospital, Peshawar/National University of Medical Sciences (NUMS) Pakistan Objective: To analyse histopathological findings in gastric biopsies of patients with dyspepsia using an updated Sydney System. Study Design: Retrospective longitudinal study. Place and Duration of Study: Histopathology Department, Najran Armed Forces Hospital (NAFH), Saudi Arabia, from Jan 2013 to Mar 2020. Methodology: A total of 408 cases whose gastric biopsies were included in the study, and their histological features were studied. Results: Among 408 patients included in the study, 191(46.8%) were males, and 217(53.2%) were females. The mean age was 37.0±15.0 years. A total of 343 patients showed gastritis, which was mild 152(44.3%), moderate 158(46.1%) and severe 33(9.6%), respectively. The activity was observed in 200(49.0%) patients. H.pylori infection was observed in 196(48.0%) patients and intestinal metaplasia in 9(2.2%) patients. Conclusion: Most of the cases with dyspepsia showed histological evidence of gastritis. However, a significant number of patients had no gastric mucosal abnormality. Therefore, adequate and timely treatment of H.pylori infection can significantly reduce related morbidity. https://pafmj.org/index.php/PAFMJ/article/view/6458GastritisHelicobacter PyloriNon-ulcer dyspepsia |
| spellingShingle | Muhammad Zubair Nabeel Khan Afridi Muhammad Amir Nawaid Hassan Tariq Akhter Ali Bajwa Naveed Khan Histopathological Analysis of Gastric Biopsies using Updated Sydney System Pakistan Armed Forces Medical Journal Gastritis Helicobacter Pylori Non-ulcer dyspepsia |
| title | Histopathological Analysis of Gastric Biopsies using Updated Sydney System |
| title_full | Histopathological Analysis of Gastric Biopsies using Updated Sydney System |
| title_fullStr | Histopathological Analysis of Gastric Biopsies using Updated Sydney System |
| title_full_unstemmed | Histopathological Analysis of Gastric Biopsies using Updated Sydney System |
| title_short | Histopathological Analysis of Gastric Biopsies using Updated Sydney System |
| title_sort | histopathological analysis of gastric biopsies using updated sydney system |
| topic | Gastritis Helicobacter Pylori Non-ulcer dyspepsia |
| url | https://pafmj.org/index.php/PAFMJ/article/view/6458 |
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