Lipoprotein (a) levels in relation to severity of coronary artery disease in north Indian patients
Background: Lipoprotein (a) [Lp (a)] is an established risk marker of coronary artery disease which is independent from other risk factors. Objective: The aim was to address the association between Lp (a) and CAD risk in North Indians. To evaluate whether high levels of lipoprotein (a) [Lp (a)] is a...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2013-01-01
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| Series: | Heart Views |
| Subjects: | |
| Online Access: | http://www.heartviews.org/article.asp?issn=1995-705X;year=2013;volume=14;issue=1;spage=12;epage=16;aulast=Ashfaq |
| _version_ | 1819079994788282368 |
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| author | Fauzia Ashfaq Pravin Kumar Goel Rishi Sethi Mohd Idrees Khan Wahid Ali Mohd Zafar Idris |
| author_facet | Fauzia Ashfaq Pravin Kumar Goel Rishi Sethi Mohd Idrees Khan Wahid Ali Mohd Zafar Idris |
| author_sort | Fauzia Ashfaq |
| collection | DOAJ |
| description | Background: Lipoprotein (a) [Lp (a)] is an established risk marker of coronary artery disease which is independent from other risk factors.
Objective: The aim was to address the association between Lp (a) and CAD risk in North Indians. To evaluate whether high levels of lipoprotein (a) [Lp (a)] is a predictor of risk and is related to the severity of CAD.
Materials and Methods: This was a cross-sectional study done on 360 patients presenting with chest pain. Coronary angiography revealed CAD in 270 patients and 90 patients without CAD. Lipoprotein (a) level, lipid profile, fasting blood glucose, anthropometric and clinical parameters were analyzed.
Results: Lipoprotein (a) 21.0 mg/dL is associated with the presence of coronary lesions ( P = 0.0001). A highly significant difference in Lp (a) levels was observed between normal coronaries vs. single-vessel disease, double-and triple-vessel disease ( P < 0.0001). Body mass index (BMI) was significantly raised in CAD group compared to normal coronary.
Conclusion: Multivariate analysis found that Lp (a) was considered an independent predictor for severity of CAD and Lp (a) levels 21.0 mg/dL are associated with severe patterns of coronary atherosclerosis. |
| first_indexed | 2024-12-21T19:37:50Z |
| format | Article |
| id | doaj.art-90d9a26bdda1492992f7eefc718931fb |
| institution | Directory Open Access Journal |
| issn | 1995-705X |
| language | English |
| last_indexed | 2024-12-21T19:37:50Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Heart Views |
| spelling | doaj.art-90d9a26bdda1492992f7eefc718931fb2022-12-21T18:52:34ZengWolters Kluwer Medknow PublicationsHeart Views1995-705X2013-01-01141121610.4103/1995-705X.107114Lipoprotein (a) levels in relation to severity of coronary artery disease in north Indian patientsFauzia AshfaqPravin Kumar GoelRishi SethiMohd Idrees KhanWahid AliMohd Zafar IdrisBackground: Lipoprotein (a) [Lp (a)] is an established risk marker of coronary artery disease which is independent from other risk factors. Objective: The aim was to address the association between Lp (a) and CAD risk in North Indians. To evaluate whether high levels of lipoprotein (a) [Lp (a)] is a predictor of risk and is related to the severity of CAD. Materials and Methods: This was a cross-sectional study done on 360 patients presenting with chest pain. Coronary angiography revealed CAD in 270 patients and 90 patients without CAD. Lipoprotein (a) level, lipid profile, fasting blood glucose, anthropometric and clinical parameters were analyzed. Results: Lipoprotein (a) 21.0 mg/dL is associated with the presence of coronary lesions ( P = 0.0001). A highly significant difference in Lp (a) levels was observed between normal coronaries vs. single-vessel disease, double-and triple-vessel disease ( P < 0.0001). Body mass index (BMI) was significantly raised in CAD group compared to normal coronary. Conclusion: Multivariate analysis found that Lp (a) was considered an independent predictor for severity of CAD and Lp (a) levels 21.0 mg/dL are associated with severe patterns of coronary atherosclerosis.http://www.heartviews.org/article.asp?issn=1995-705X;year=2013;volume=14;issue=1;spage=12;epage=16;aulast=AshfaqAngiographyatherosclerosislipoprotein (a)triglyceride |
| spellingShingle | Fauzia Ashfaq Pravin Kumar Goel Rishi Sethi Mohd Idrees Khan Wahid Ali Mohd Zafar Idris Lipoprotein (a) levels in relation to severity of coronary artery disease in north Indian patients Heart Views Angiography atherosclerosis lipoprotein (a) triglyceride |
| title | Lipoprotein (a) levels in relation to severity of coronary artery disease in north Indian patients |
| title_full | Lipoprotein (a) levels in relation to severity of coronary artery disease in north Indian patients |
| title_fullStr | Lipoprotein (a) levels in relation to severity of coronary artery disease in north Indian patients |
| title_full_unstemmed | Lipoprotein (a) levels in relation to severity of coronary artery disease in north Indian patients |
| title_short | Lipoprotein (a) levels in relation to severity of coronary artery disease in north Indian patients |
| title_sort | lipoprotein a levels in relation to severity of coronary artery disease in north indian patients |
| topic | Angiography atherosclerosis lipoprotein (a) triglyceride |
| url | http://www.heartviews.org/article.asp?issn=1995-705X;year=2013;volume=14;issue=1;spage=12;epage=16;aulast=Ashfaq |
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