Acute Poisoning Readmissions to an Emergency Department of a Tertiary Hospital: Evaluation through an Active Toxicovigilance Program

The aim of this study is to investigate hospital readmissions during 1 year after acute poisoning cases (APC), analyze the temporal behavior of early readmissions (ER) (in the month after the index episode) and predict possible ER. A descriptive analysis of the patients with APC assisted between 201...

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Main Authors: Raúl Muñoz Romo, Alberto M. Borobia Pérez, Rosa Mayayo Alvira, Mikel Urroz, Amelia Rodríguez Mariblanca, Francisco J. Guijarro Eguinoa, Lucia Diaz García, Julio Cobo Mora, Angelica Rivera, Rosario Torres, Antonio J. Carcas Sansuán
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/11/15/4508
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author Raúl Muñoz Romo
Alberto M. Borobia Pérez
Rosa Mayayo Alvira
Mikel Urroz
Amelia Rodríguez Mariblanca
Francisco J. Guijarro Eguinoa
Lucia Diaz García
Julio Cobo Mora
Angelica Rivera
Rosario Torres
Antonio J. Carcas Sansuán
author_facet Raúl Muñoz Romo
Alberto M. Borobia Pérez
Rosa Mayayo Alvira
Mikel Urroz
Amelia Rodríguez Mariblanca
Francisco J. Guijarro Eguinoa
Lucia Diaz García
Julio Cobo Mora
Angelica Rivera
Rosario Torres
Antonio J. Carcas Sansuán
author_sort Raúl Muñoz Romo
collection DOAJ
description The aim of this study is to investigate hospital readmissions during 1 year after acute poisoning cases (APC), analyze the temporal behavior of early readmissions (ER) (in the month after the index episode) and predict possible ER. A descriptive analysis of the patients with APC assisted between 2011 and 2016 in the Emergency Department of Hospital La Paz is presented, and various methods of inferential statistics were applied and confirmed by Bayesian analysis in order to evaluate factors associated with total and early readmissions. Out of the 4693 cases of APC included, 968 (20.6%) presented, at least one readmission and 476 (10.1%) of them were ER. The mean age of APC with readmission was 41 years (12.7 SD), 78.9% had previous psychiatric pathology and 44.7% had a clinical history of alcohol addiction. Accidental poisoning has been a protective factor for readmission (OR 0.50; 0.26–0.96). Type of toxin (“drug of abuse” OR 8.88; 1.17–67.25), history of addiction (OR 1.93; 1.18–3.10) and psychiatric history (OR 3.30; 2.53–4.30) are risk factors for readmissions during the first year. Women showed three or more readmissions in a year. The results of the study allow for identification of the predictors for the different numbers of readmissions in the year after the index APC, as well as for ERs.
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spelling doaj.art-90dc3053f75040aeb11d430f0b44fc1e2023-12-01T22:59:54ZengMDPI AGJournal of Clinical Medicine2077-03832022-08-011115450810.3390/jcm11154508Acute Poisoning Readmissions to an Emergency Department of a Tertiary Hospital: Evaluation through an Active Toxicovigilance ProgramRaúl Muñoz Romo0Alberto M. Borobia Pérez1Rosa Mayayo Alvira2Mikel Urroz3Amelia Rodríguez Mariblanca4Francisco J. Guijarro Eguinoa5Lucia Diaz García6Julio Cobo Mora7Angelica Rivera8Rosario Torres9Antonio J. Carcas Sansuán10Clinical Pharmacology Department, University Hospital Paz-IdiPAZ, Universidad Autónoma de Madrid, 28049 Madrid, SpainClinical Pharmacology Department, University Hospital Paz-IdiPAZ, Universidad Autónoma de Madrid, 28049 Madrid, SpainClinical Toxicology Unit, University Hospital Paz, 28046 Madrid, SpainClinical Pharmacology Department, University Hospital Paz-IdiPAZ, Universidad Autónoma de Madrid, 28049 Madrid, SpainClinical Toxicology Unit, University Hospital Paz, 28046 Madrid, SpainClinical Pharmacology Department, University Hospital Paz-IdiPAZ, Universidad Autónoma de Madrid, 28049 Madrid, SpainClinical Pharmacology Department, University Hospital Paz-IdiPAZ, Universidad Autónoma de Madrid, 28049 Madrid, SpainEmergency Department, University Hospital Paz, 28046 Madrid, SpainClinical Toxicology Unit, University Hospital Paz, 28046 Madrid, SpainClinical Toxicology Unit, University Hospital Paz, 28046 Madrid, SpainClinical Pharmacology Department, University Hospital Paz-IdiPAZ, Universidad Autónoma de Madrid, 28049 Madrid, SpainThe aim of this study is to investigate hospital readmissions during 1 year after acute poisoning cases (APC), analyze the temporal behavior of early readmissions (ER) (in the month after the index episode) and predict possible ER. A descriptive analysis of the patients with APC assisted between 2011 and 2016 in the Emergency Department of Hospital La Paz is presented, and various methods of inferential statistics were applied and confirmed by Bayesian analysis in order to evaluate factors associated with total and early readmissions. Out of the 4693 cases of APC included, 968 (20.6%) presented, at least one readmission and 476 (10.1%) of them were ER. The mean age of APC with readmission was 41 years (12.7 SD), 78.9% had previous psychiatric pathology and 44.7% had a clinical history of alcohol addiction. Accidental poisoning has been a protective factor for readmission (OR 0.50; 0.26–0.96). Type of toxin (“drug of abuse” OR 8.88; 1.17–67.25), history of addiction (OR 1.93; 1.18–3.10) and psychiatric history (OR 3.30; 2.53–4.30) are risk factors for readmissions during the first year. Women showed three or more readmissions in a year. The results of the study allow for identification of the predictors for the different numbers of readmissions in the year after the index APC, as well as for ERs.https://www.mdpi.com/2077-0383/11/15/4508acute intoxicationhospital readmissionquality of caretoxicological surveillanceclinical toxicologytoxicovigilance
spellingShingle Raúl Muñoz Romo
Alberto M. Borobia Pérez
Rosa Mayayo Alvira
Mikel Urroz
Amelia Rodríguez Mariblanca
Francisco J. Guijarro Eguinoa
Lucia Diaz García
Julio Cobo Mora
Angelica Rivera
Rosario Torres
Antonio J. Carcas Sansuán
Acute Poisoning Readmissions to an Emergency Department of a Tertiary Hospital: Evaluation through an Active Toxicovigilance Program
Journal of Clinical Medicine
acute intoxication
hospital readmission
quality of care
toxicological surveillance
clinical toxicology
toxicovigilance
title Acute Poisoning Readmissions to an Emergency Department of a Tertiary Hospital: Evaluation through an Active Toxicovigilance Program
title_full Acute Poisoning Readmissions to an Emergency Department of a Tertiary Hospital: Evaluation through an Active Toxicovigilance Program
title_fullStr Acute Poisoning Readmissions to an Emergency Department of a Tertiary Hospital: Evaluation through an Active Toxicovigilance Program
title_full_unstemmed Acute Poisoning Readmissions to an Emergency Department of a Tertiary Hospital: Evaluation through an Active Toxicovigilance Program
title_short Acute Poisoning Readmissions to an Emergency Department of a Tertiary Hospital: Evaluation through an Active Toxicovigilance Program
title_sort acute poisoning readmissions to an emergency department of a tertiary hospital evaluation through an active toxicovigilance program
topic acute intoxication
hospital readmission
quality of care
toxicological surveillance
clinical toxicology
toxicovigilance
url https://www.mdpi.com/2077-0383/11/15/4508
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