Report of a phase 1 clinical trial for safety assessment of human placental mesenchymal stem cells therapy in patients with critical limb ischemia (CLI)

Report of a phase 1 clinical trial for safety assessment of human placental mesenchymal stem cells therapy in patients with critical limb ischemia (CLI)

Abstract Background Critical limb ischemia (CLI) is associated with increased risk of tissue loss, leading to significant morbidity and mortality. Therapeutic angiogenesis using cell-based treatments, notably mesenchymal stem cells (MSCs), is essential for enhancing blood flow to ischemic areas in s...

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Bibliographic Details
Main Authors: Zeinab Shirbaghaee, Saeed Heidari Keshel, Mehdi Rasouli, Majid Valizadeh, Seyed Saeed Hashemi Nazari, Mohammad Hassani, Masoud Soleimani
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Stem Cell Research & Therapy
Subjects:
Critical limb ischemia
Peripheral artery disease
Buerger
Placenta
Mesenchymal stem cell
Clinical trial
Online Access:https://doi.org/10.1186/s13287-023-03390-9

Internet

https://doi.org/10.1186/s13287-023-03390-9

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