Exposure to long-term source-specific transportation noise and incident breast cancer: A pooled study of eight Nordic cohorts
Background: Environmental noise is an important environmental exposure that can affect health. An association between transportation noise and breast cancer incidence has been suggested, although current evidence is limited. We investigated the pooled association between long-term exposure to transp...
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Elsevier
2023-08-01
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| Series: | Environment International |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0160412023003811 |
| _version_ | 1828718400552042496 |
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| author | Jesse D. Thacher Anna Oudin Erin Flanagan Kristoffer Mattisson Maria Albin Nina Roswall Andrei Pyko Gunn Marit Aasvang Zorana J. Andersen Signe Borgquist Jørgen Brandt Karin Broberg Thomas Cole-Hunter Charlotta Eriksson Kristina Eneroth Hrafnhildur Gudjonsdottir Emilie Helte Matthias Ketzel Timo Lanki Youn-Hee Lim Karin Leander Petter Ljungman Jonas Manjer Satu Männistö Ole Raaschou-Nielsen Göran Pershagen Debora Rizzuto Malte Sandsveden Jenny Selander Mette K. Simonsen Lara Stucki Mårten Spanne Leo Stockfelt Anne Tjønneland Tarja Yli-Tuomi Pekka Tiittanen Victor H. Valencia Mikael Ögren Agneta Åkesson Mette Sørensen |
| author_facet | Jesse D. Thacher Anna Oudin Erin Flanagan Kristoffer Mattisson Maria Albin Nina Roswall Andrei Pyko Gunn Marit Aasvang Zorana J. Andersen Signe Borgquist Jørgen Brandt Karin Broberg Thomas Cole-Hunter Charlotta Eriksson Kristina Eneroth Hrafnhildur Gudjonsdottir Emilie Helte Matthias Ketzel Timo Lanki Youn-Hee Lim Karin Leander Petter Ljungman Jonas Manjer Satu Männistö Ole Raaschou-Nielsen Göran Pershagen Debora Rizzuto Malte Sandsveden Jenny Selander Mette K. Simonsen Lara Stucki Mårten Spanne Leo Stockfelt Anne Tjønneland Tarja Yli-Tuomi Pekka Tiittanen Victor H. Valencia Mikael Ögren Agneta Åkesson Mette Sørensen |
| author_sort | Jesse D. Thacher |
| collection | DOAJ |
| description | Background: Environmental noise is an important environmental exposure that can affect health. An association between transportation noise and breast cancer incidence has been suggested, although current evidence is limited. We investigated the pooled association between long-term exposure to transportation noise and breast cancer incidence. Methods: Pooled data from eight Nordic cohorts provided a study population of 111,492 women. Road, railway, and aircraft noise were modelled at residential addresses. Breast cancer incidence (all, estrogen receptor (ER) positive, and ER negative) was derived from cancer registries. Hazard ratios (HR) were estimated using Cox Proportional Hazards Models, adjusting main models for sociodemographic and lifestyle variables together with long-term exposure to air pollution. Results: A total of 93,859 women were included in the analyses, of whom 5,875 developed breast cancer. The median (5th–95th percentile) 5-year residential road traffic noise was 54.8 (40.0–67.8) dB Lden, and among those exposed, the median railway noise was 51.0 (41.2–65.8) dB Lden. We observed a pooled HR for breast cancer (95 % confidence interval (CI)) of 1.03 (0.99–1.06) per 10 dB increase in 5-year mean exposure to road traffic noise, and 1.03 (95 % CI: 0.96–1.11) for railway noise, after adjustment for lifestyle and sociodemographic covariates. HRs remained unchanged in analyses with further adjustment for PM2.5 and attenuated when adjusted for NO2 (HRs from 1.02 to 1.01), in analyses using the same sample. For aircraft noise, no association was observed. The associations did not vary by ER status for any noise source. In analyses using <60 dB as a cutoff, we found HRs of 1.08 (0.99–1.18) for road traffic and 1.19 (0.95–1.49) for railway noise. Conclusions: We found weak associations between road and railway noise and breast cancer risk. More high-quality prospective studies are needed, particularly among those exposed to railway and aircraft noise before conclusions regarding noise as a risk factor for breast cancer can be made. |
| first_indexed | 2024-03-12T14:43:09Z |
| format | Article |
| id | doaj.art-90dfd8ff91734759bdde746a42bb0608 |
| institution | Directory Open Access Journal |
| issn | 0160-4120 |
| language | English |
| last_indexed | 2024-03-12T14:43:09Z |
| publishDate | 2023-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Environment International |
| spelling | doaj.art-90dfd8ff91734759bdde746a42bb06082023-08-16T04:26:27ZengElsevierEnvironment International0160-41202023-08-01178108108Exposure to long-term source-specific transportation noise and incident breast cancer: A pooled study of eight Nordic cohortsJesse D. Thacher0Anna Oudin1Erin Flanagan2Kristoffer Mattisson3Maria Albin4Nina Roswall5Andrei Pyko6Gunn Marit Aasvang7Zorana J. Andersen8Signe Borgquist9Jørgen Brandt10Karin Broberg11Thomas Cole-Hunter12Charlotta Eriksson13Kristina Eneroth14Hrafnhildur Gudjonsdottir15Emilie Helte16Matthias Ketzel17Timo Lanki18Youn-Hee Lim19Karin Leander20Petter Ljungman21Jonas Manjer22Satu Männistö23Ole Raaschou-Nielsen24Göran Pershagen25Debora Rizzuto26Malte Sandsveden27Jenny Selander28Mette K. Simonsen29Lara Stucki30Mårten Spanne31Leo Stockfelt32Anne Tjønneland33Tarja Yli-Tuomi34Pekka Tiittanen35Victor H. Valencia36Mikael Ögren37Agneta Åkesson38Mette Sørensen39Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden; Corresponding author.Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden; Section for Sustainable Health, Umeå University, SwedenDivision of Occupational and Environmental Medicine, Lund University, Lund, SwedenDivision of Occupational and Environmental Medicine, Lund University, Lund, SwedenDivision of Occupational and Environmental Medicine, Lund University, Lund, Sweden; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, SwedenDanish Cancer Society Research Centre, Strandboulevarden 49, 2100 Copenhagen Ø, DenmarkInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Center for Occupational and Environmental Medicine, Region Stockholm, Stockholm, SwedenDepartment of Air Quality and Noise, Norwegian Institute of Public Health, Oslo, NorwayDepartment of Public Health, University of Copenhagen, Copenhagen, DenmarkDepartment of Oncology, Aarhus University Hospital, Aarhus University, Aarhus, DenmarkDepartment of Environmental Science, Aarhus University, Roskilde, DenmarkDivision of Occupational and Environmental Medicine, Lund University, Lund, SwedenDepartment of Public Health, University of Copenhagen, Copenhagen, DenmarkInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Center for Occupational and Environmental Medicine, Region Stockholm, Stockholm, SwedenEnvironment and Health Administration, Stockholm, SwedenCentre for Epidemiology and Community Medicine, Region Stockholm, Stockholm, Sweden; Department of Global Public Health, Karolinska Institutet, Stockholm, SwedenInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, SwedenDepartment of Environmental Science, Aarhus University, Roskilde, Denmark; Global Centre for Clean Air Research (GCARE), University of Surrey, Guildford, United KingdomDepartment of Health Security, Finnish Institute for Health and Welfare, Kuopio, Finland; School of Medicine, University of Eastern Finland, Kuopio, Finland; Department of Environmental and Biological Sciences, University of Eastern Finland, Kuopio, FinlandDepartment of Public Health, University of Copenhagen, Copenhagen, DenmarkInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, SwedenInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Department of Cardiology, Danderyd Hospital, Stockholm, SwedenDepartment of Surgery, Skåne University Hospital Malmö, Lund University, Malmö, SwedenDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, FinlandDanish Cancer Society Research Centre, Strandboulevarden 49, 2100 Copenhagen Ø, Denmark; Department of Environmental Science, Aarhus University, Roskilde, DenmarkInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, SwedenAging Research Centre, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, SwedenDepartment of Clinical Sciences Malmö, Lund University, SwedenInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, SwedenDepartment of Neurology and the Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, DenmarkInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, SwedenEnvironment Department, City of Malmö, Malmö, SwedenDepartment of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden; Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, SwedenDanish Cancer Society Research Centre, Strandboulevarden 49, 2100 Copenhagen Ø, Denmark; Department of Public Health, University of Copenhagen, Copenhagen, DenmarkDepartment of Health Security, Finnish Institute for Health and Welfare, Kuopio, FinlandDepartment of Health Security, Finnish Institute for Health and Welfare, Kuopio, FinlandDepartment of Environmental Science, Aarhus University, Roskilde, Denmark; UTE University, Quito, EcuadorDepartment of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden; Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, SwedenInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, SwedenDanish Cancer Society Research Centre, Strandboulevarden 49, 2100 Copenhagen Ø, Denmark; Department of Natural Science and Environment, Roskilde University, DenmarkBackground: Environmental noise is an important environmental exposure that can affect health. An association between transportation noise and breast cancer incidence has been suggested, although current evidence is limited. We investigated the pooled association between long-term exposure to transportation noise and breast cancer incidence. Methods: Pooled data from eight Nordic cohorts provided a study population of 111,492 women. Road, railway, and aircraft noise were modelled at residential addresses. Breast cancer incidence (all, estrogen receptor (ER) positive, and ER negative) was derived from cancer registries. Hazard ratios (HR) were estimated using Cox Proportional Hazards Models, adjusting main models for sociodemographic and lifestyle variables together with long-term exposure to air pollution. Results: A total of 93,859 women were included in the analyses, of whom 5,875 developed breast cancer. The median (5th–95th percentile) 5-year residential road traffic noise was 54.8 (40.0–67.8) dB Lden, and among those exposed, the median railway noise was 51.0 (41.2–65.8) dB Lden. We observed a pooled HR for breast cancer (95 % confidence interval (CI)) of 1.03 (0.99–1.06) per 10 dB increase in 5-year mean exposure to road traffic noise, and 1.03 (95 % CI: 0.96–1.11) for railway noise, after adjustment for lifestyle and sociodemographic covariates. HRs remained unchanged in analyses with further adjustment for PM2.5 and attenuated when adjusted for NO2 (HRs from 1.02 to 1.01), in analyses using the same sample. For aircraft noise, no association was observed. The associations did not vary by ER status for any noise source. In analyses using <60 dB as a cutoff, we found HRs of 1.08 (0.99–1.18) for road traffic and 1.19 (0.95–1.49) for railway noise. Conclusions: We found weak associations between road and railway noise and breast cancer risk. More high-quality prospective studies are needed, particularly among those exposed to railway and aircraft noise before conclusions regarding noise as a risk factor for breast cancer can be made.http://www.sciencedirect.com/science/article/pii/S0160412023003811NoiseTraffic noiseRailway noiseAircraft noiseAir pollutionTraffic |
| spellingShingle | Jesse D. Thacher Anna Oudin Erin Flanagan Kristoffer Mattisson Maria Albin Nina Roswall Andrei Pyko Gunn Marit Aasvang Zorana J. Andersen Signe Borgquist Jørgen Brandt Karin Broberg Thomas Cole-Hunter Charlotta Eriksson Kristina Eneroth Hrafnhildur Gudjonsdottir Emilie Helte Matthias Ketzel Timo Lanki Youn-Hee Lim Karin Leander Petter Ljungman Jonas Manjer Satu Männistö Ole Raaschou-Nielsen Göran Pershagen Debora Rizzuto Malte Sandsveden Jenny Selander Mette K. Simonsen Lara Stucki Mårten Spanne Leo Stockfelt Anne Tjønneland Tarja Yli-Tuomi Pekka Tiittanen Victor H. Valencia Mikael Ögren Agneta Åkesson Mette Sørensen Exposure to long-term source-specific transportation noise and incident breast cancer: A pooled study of eight Nordic cohorts Environment International Noise Traffic noise Railway noise Aircraft noise Air pollution Traffic |
| title | Exposure to long-term source-specific transportation noise and incident breast cancer: A pooled study of eight Nordic cohorts |
| title_full | Exposure to long-term source-specific transportation noise and incident breast cancer: A pooled study of eight Nordic cohorts |
| title_fullStr | Exposure to long-term source-specific transportation noise and incident breast cancer: A pooled study of eight Nordic cohorts |
| title_full_unstemmed | Exposure to long-term source-specific transportation noise and incident breast cancer: A pooled study of eight Nordic cohorts |
| title_short | Exposure to long-term source-specific transportation noise and incident breast cancer: A pooled study of eight Nordic cohorts |
| title_sort | exposure to long term source specific transportation noise and incident breast cancer a pooled study of eight nordic cohorts |
| topic | Noise Traffic noise Railway noise Aircraft noise Air pollution Traffic |
| url | http://www.sciencedirect.com/science/article/pii/S0160412023003811 |
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