Bmal1 knockdown in the left stellate ganglion inhibits neural activity and prevents ventricular arrhythmias after myocardial ischemia

Bmal1 knockdown in the left stellate ganglion inhibits neural activity and prevents ventricular arrhythmias after myocardial ischemia

ObjectivesThe neural activity of the left stellate ganglion (LSG) is closely related to the occurrence of ventricular arrhythmias (VAs). Bmal1 modulates genes associated with neural activity in the central nervous system. However, few studies indicated the role of Bmal1 in the LSG and the subsequent...

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Main Authors: Zhongyang Yu, Zhihao Liu, Liying Jiao, Song Zhang, Liqing Nie, Yueyi Wang, Liping Zhou, Yuhong Wang, Zihan Liu, Xiao Xu, Zeyan Li, Yuyang Zhou, Huixin Zhou, Rui Li, Chen Peng, Lilei Yu, Hong Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Bmal1
left stellate ganglion
myocardial ischemia
ventricular arrhythmias
transcriptomics
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.937608/full

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