Bony-based and prostate-based image guidance for lo-calized prostate cancer radiotherapy
An important modality for the treatment of prostate cancer is teletherapy. The use of image-guided radiotherapy (IGRT) is a valuable tool in this treatment. This study retrospectively compared how repositioning the patient based on bone structure (B-ISO) and the prostate itself (P-ISO) affected the...
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| Format: | Article |
| Language: | English |
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Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR)
2020-03-01
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| Series: | Brazilian Journal of Radiation Sciences |
| Subjects: | |
| Online Access: | https://bjrs.org.br/revista/index.php/REVISTA/article/view/1175 |
| _version_ | 1797985920928972800 |
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| author | Saulo Santos Fortes Luiz Antonio Ribeiro da Rosa |
| author_facet | Saulo Santos Fortes Luiz Antonio Ribeiro da Rosa |
| author_sort | Saulo Santos Fortes |
| collection | DOAJ |
| description | An important modality for the treatment of prostate cancer is teletherapy. The use of image-guided radiotherapy (IGRT) is a valuable tool in this treatment. This study retrospectively compared how repositioning the patient based on bone structure (B-ISO) and the prostate itself (P-ISO) affected the volumetric dose in the rectum, bladder, and clinical treatment volume (CTV). Additionally, the probability of normal tissue complication (NTCP) for the rectum was computed. We evaluated 155 cone-beam computed tomography (CBCT) from 8 patients. The treatment plans used beam modulation techniques. The planning target volume (PTV) margin adopted in both scenarios was 1 cm. The organs of interest were outlined over each CBCT and then treatment plans were applied so that the absorbed dose could be computed. NTCP values were calculated for the rectum. Analyzing dose-volume metrics published by the Quantitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC), there was no significant difference between the two repositioning strategies for the rectum and bladder. There was a slight degradation in CTV coverage for the B-ISO strategy, but still with adequate coverage. Analysis of the uniform equivalent dose (EUD) and NTCP for the rectum showed little sensitivity to the strategy used. The present study showed that the use of CBCT in radiotherapy for prostate cancer treatment did not significantly improve volumetric doses for the rectum, bladder, and CTV, as well as NTCP for the rectum. |
| first_indexed | 2024-04-11T07:25:33Z |
| format | Article |
| id | doaj.art-90e31a6647b746058c7126ac09aeef29 |
| institution | Directory Open Access Journal |
| issn | 2319-0612 |
| language | English |
| last_indexed | 2024-04-11T07:25:33Z |
| publishDate | 2020-03-01 |
| publisher | Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR) |
| record_format | Article |
| series | Brazilian Journal of Radiation Sciences |
| spelling | doaj.art-90e31a6647b746058c7126ac09aeef292022-12-22T04:37:05ZengBrazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR)Brazilian Journal of Radiation Sciences2319-06122020-03-018110.15392/bjrs.v8i1.1175Bony-based and prostate-based image guidance for lo-calized prostate cancer radiotherapySaulo Santos Fortes0Luiz Antonio Ribeiro da Rosa1Instituto Nacional de Câncer José Alencar Gomes da SilvaInstituto de Radioproteção e DosimetriaAn important modality for the treatment of prostate cancer is teletherapy. The use of image-guided radiotherapy (IGRT) is a valuable tool in this treatment. This study retrospectively compared how repositioning the patient based on bone structure (B-ISO) and the prostate itself (P-ISO) affected the volumetric dose in the rectum, bladder, and clinical treatment volume (CTV). Additionally, the probability of normal tissue complication (NTCP) for the rectum was computed. We evaluated 155 cone-beam computed tomography (CBCT) from 8 patients. The treatment plans used beam modulation techniques. The planning target volume (PTV) margin adopted in both scenarios was 1 cm. The organs of interest were outlined over each CBCT and then treatment plans were applied so that the absorbed dose could be computed. NTCP values were calculated for the rectum. Analyzing dose-volume metrics published by the Quantitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC), there was no significant difference between the two repositioning strategies for the rectum and bladder. There was a slight degradation in CTV coverage for the B-ISO strategy, but still with adequate coverage. Analysis of the uniform equivalent dose (EUD) and NTCP for the rectum showed little sensitivity to the strategy used. The present study showed that the use of CBCT in radiotherapy for prostate cancer treatment did not significantly improve volumetric doses for the rectum, bladder, and CTV, as well as NTCP for the rectum.https://bjrs.org.br/revista/index.php/REVISTA/article/view/1175prostate radiotherapycone-beam computed tomographyrepositioning strategy |
| spellingShingle | Saulo Santos Fortes Luiz Antonio Ribeiro da Rosa Bony-based and prostate-based image guidance for lo-calized prostate cancer radiotherapy Brazilian Journal of Radiation Sciences prostate radiotherapy cone-beam computed tomography repositioning strategy |
| title | Bony-based and prostate-based image guidance for lo-calized prostate cancer radiotherapy |
| title_full | Bony-based and prostate-based image guidance for lo-calized prostate cancer radiotherapy |
| title_fullStr | Bony-based and prostate-based image guidance for lo-calized prostate cancer radiotherapy |
| title_full_unstemmed | Bony-based and prostate-based image guidance for lo-calized prostate cancer radiotherapy |
| title_short | Bony-based and prostate-based image guidance for lo-calized prostate cancer radiotherapy |
| title_sort | bony based and prostate based image guidance for lo calized prostate cancer radiotherapy |
| topic | prostate radiotherapy cone-beam computed tomography repositioning strategy |
| url | https://bjrs.org.br/revista/index.php/REVISTA/article/view/1175 |
| work_keys_str_mv | AT saulosantosfortes bonybasedandprostatebasedimageguidanceforlocalizedprostatecancerradiotherapy AT luizantonioribeirodarosa bonybasedandprostatebasedimageguidanceforlocalizedprostatecancerradiotherapy |