Penile Cancer in Cali, Colombia: 10 Years of Casuistry in a Tertiary Referral Center of a Middle-Income Country
Background: Penile cancer is a rare disease in Colombia; in Cali, it represents 0.7% of all cancers. Penile cancer has been associated with old age, bad hygiene, smoking and lack of circumcision. This study aimed to describe the sociodemographic and clinica characteristics of patients with penile c...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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University Library System, University of Pittsburgh
2014-09-01
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| Series: | International Journal of Medical Students |
| Subjects: | |
| Online Access: | http://ijms.info/IJMS/article/view/98 |
| _version_ | 1797727437781467136 |
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| author | Lina M. Rengifo Maria del M. Herrera Angie L. Rincon-Jimenez Alberto J. Bermudez-Pupo Francisco J. Bonilla-Escobar |
| author_facet | Lina M. Rengifo Maria del M. Herrera Angie L. Rincon-Jimenez Alberto J. Bermudez-Pupo Francisco J. Bonilla-Escobar |
| author_sort | Lina M. Rengifo |
| collection | DOAJ |
| description | Background: Penile cancer is a rare disease in Colombia; in Cali, it represents 0.7% of all cancers. Penile cancer has been associated with old age, bad hygiene, smoking and lack of circumcision. This study aimed to describe the sociodemographic and clinica characteristics of patients with penile cancer who consulted to a tertiary referral hospital. Methods: A case series of all penile cance cases at a reference institution in Cali during 2001-2010. Socioeconomic, demographic and clinical features of patients were described, and bivariate analyses were carried out. Results: There were 46 penile cancer cases. The average age was 60 ± 16.9 years. The main reason for consultation was an exophytic mass on the penis (75.0%). The most common location was the glans (69.6%), and the more frequent histology type was the squamous cell carcinoma (95.7%). With regard to risk factors, 65.5% of the patients had history of smoking and90.9% did not have circumcision. Patients who underwent radical amputation had higher rates of positive nodes (55% vs. 13.5%, p=0.015) and ulcerative lesions (77.8% vs. 29.7%, p=0.018) than those who did not have the procedure done. Recurrence was associated with the presence of lymphadenopathy (p=0.02) and history of circumcision (p=0.015). Conclusion: Most of the patients with penile cancer found in this study had old age, history of tobacco use and lack of circumcision. Patients who presented with lymph node metastasis had to undergo more radical procedures and suffered a greater rate of recurrence compared with those without lymph node involvement. Robust studies to determine the risk factors among low-income populations are required. |
| first_indexed | 2024-03-12T10:59:43Z |
| format | Article |
| id | doaj.art-90e42e230b1e4d78af6e1c9f65f2620d |
| institution | Directory Open Access Journal |
| issn | 2076-6327 |
| language | English |
| last_indexed | 2024-03-12T10:59:43Z |
| publishDate | 2014-09-01 |
| publisher | University Library System, University of Pittsburgh |
| record_format | Article |
| series | International Journal of Medical Students |
| spelling | doaj.art-90e42e230b1e4d78af6e1c9f65f2620d2023-09-02T05:56:40ZengUniversity Library System, University of PittsburghInternational Journal of Medical Students2076-63272014-09-012310911410.5195/ijms.2014.9898Penile Cancer in Cali, Colombia: 10 Years of Casuistry in a Tertiary Referral Center of a Middle-Income CountryLina M. Rengifo0Maria del M. Herrera1Angie L. Rincon-Jimenez2Alberto J. Bermudez-Pupo3Francisco J. Bonilla-Escobar4Fifth year Medical Student, Faculty of Health, Universidad del Valle, Cali, ColombiaFifth year Medical Student, Faculty of Health, Universidad del Valle, Cali, Colombia.Fifth year Medical Student, Faculty of Health, Universidad del Valle, Cali, Colombia.MD, Urologist, Professor, Urology Department, Universidad del Valle, Hospital Universitario del Valle "Evaristo Garcia" ESE, Cali, ColombiaMD, MSc(c), Editor in Chief IJMS. Research Associate, Cisalva Institute, Universidad del Valle, Cali, Colombia.Background: Penile cancer is a rare disease in Colombia; in Cali, it represents 0.7% of all cancers. Penile cancer has been associated with old age, bad hygiene, smoking and lack of circumcision. This study aimed to describe the sociodemographic and clinica characteristics of patients with penile cancer who consulted to a tertiary referral hospital. Methods: A case series of all penile cance cases at a reference institution in Cali during 2001-2010. Socioeconomic, demographic and clinical features of patients were described, and bivariate analyses were carried out. Results: There were 46 penile cancer cases. The average age was 60 ± 16.9 years. The main reason for consultation was an exophytic mass on the penis (75.0%). The most common location was the glans (69.6%), and the more frequent histology type was the squamous cell carcinoma (95.7%). With regard to risk factors, 65.5% of the patients had history of smoking and90.9% did not have circumcision. Patients who underwent radical amputation had higher rates of positive nodes (55% vs. 13.5%, p=0.015) and ulcerative lesions (77.8% vs. 29.7%, p=0.018) than those who did not have the procedure done. Recurrence was associated with the presence of lymphadenopathy (p=0.02) and history of circumcision (p=0.015). Conclusion: Most of the patients with penile cancer found in this study had old age, history of tobacco use and lack of circumcision. Patients who presented with lymph node metastasis had to undergo more radical procedures and suffered a greater rate of recurrence compared with those without lymph node involvement. Robust studies to determine the risk factors among low-income populations are required.http://ijms.info/IJMS/article/view/98penile neoplasmscircumcisionmalesmokingdeveloping countries |
| spellingShingle | Lina M. Rengifo Maria del M. Herrera Angie L. Rincon-Jimenez Alberto J. Bermudez-Pupo Francisco J. Bonilla-Escobar Penile Cancer in Cali, Colombia: 10 Years of Casuistry in a Tertiary Referral Center of a Middle-Income Country International Journal of Medical Students penile neoplasms circumcision male smoking developing countries |
| title | Penile Cancer in Cali, Colombia: 10 Years of Casuistry in a Tertiary Referral Center of a Middle-Income Country |
| title_full | Penile Cancer in Cali, Colombia: 10 Years of Casuistry in a Tertiary Referral Center of a Middle-Income Country |
| title_fullStr | Penile Cancer in Cali, Colombia: 10 Years of Casuistry in a Tertiary Referral Center of a Middle-Income Country |
| title_full_unstemmed | Penile Cancer in Cali, Colombia: 10 Years of Casuistry in a Tertiary Referral Center of a Middle-Income Country |
| title_short | Penile Cancer in Cali, Colombia: 10 Years of Casuistry in a Tertiary Referral Center of a Middle-Income Country |
| title_sort | penile cancer in cali colombia 10 years of casuistry in a tertiary referral center of a middle income country |
| topic | penile neoplasms circumcision male smoking developing countries |
| url | http://ijms.info/IJMS/article/view/98 |
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