Can the 3rd Hour Value of 100 g Oral Glucose Tolerance Test Be Ignored in the Diagnosis of Gestational Diabetes Mellitus?
OBJECTIVE: To investigate whether the 3rd hour value of 100 g oral glucose tolerance test (OGTT) can be ignored when diagnosing gestational diabetes. STUDY DESIGN: During the first 8 months of 2010, 6909 patients between 24 and 28 weeks’ of gestation were screened with 50 g glucose challenge test an...
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| Format: | Article |
| Language: | English |
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Medical Network
2016-05-01
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| Series: | Gynecology Obstetrics & Reproductive Medicine |
| Subjects: | |
| Online Access: | http://gorm.com.tr/index.php/GORM/article/view/209 |
| _version_ | 1797920437215166464 |
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| author | Mehmet Metin Altay Serdinç Özdoğan Aytaç Tohma Sertaç Esin Okyar Erol Orhan Gelişen Melih Akkuş Sinan Karadeniz |
| author_facet | Mehmet Metin Altay Serdinç Özdoğan Aytaç Tohma Sertaç Esin Okyar Erol Orhan Gelişen Melih Akkuş Sinan Karadeniz |
| author_sort | Mehmet Metin Altay |
| collection | DOAJ |
| description | OBJECTIVE: To investigate whether the 3rd hour value of 100 g oral glucose tolerance test (OGTT) can be ignored when diagnosing gestational diabetes.
STUDY DESIGN: During the first 8 months of 2010, 6909 patients between 24 and 28 weeks’ of gestation were screened with 50 g glucose challenge test and 140 mg/dl or higher plasma glucose levels were further evaluated with 100 g OGTT to diagnose gestational diabetes mellitus (GDM). 1195 patients’ test results were acquired for this retrospective study. For the 100 g OGTT fasting plasma glucose cut-off value was 105 mg/dl, 1 hour cut-off value was 190 mg/dl, 2 hour cut-off value was 165 mg/dl and 3 hour cut-off value was 145 mg/dl. Patients with 2 or more values above the cut-off level were diagnosed as GDM.
RESULTS: Out of 1195, 124 patients (10.4%) were diagnosed as having GDM. 65 patients (52.4%) had high values of first and second hours; 33 patients (26.6%) had high values of first, second and third hours; 19 patients (15.4%) had second and third hours high values; 7 patients (5.6%) had first and third hours high values of 100 gr OGTT out of those 124 patients.
CONCLUSION: 79% of the patients were diagnosed with first and second hour test results but 21% of the patients were diagnosed with blood glucose levels above the third hour cut-off level. Thus, considering the difficulties of 100 gr. OGTT, third hour values is of diagnostic value and cannot be ignored. |
| first_indexed | 2024-04-10T14:01:11Z |
| format | Article |
| id | doaj.art-90ebab38607141f4a7874d7987dd62f8 |
| institution | Directory Open Access Journal |
| issn | 1300-4751 |
| language | English |
| last_indexed | 2024-04-10T14:01:11Z |
| publishDate | 2016-05-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj.art-90ebab38607141f4a7874d7987dd62f82023-02-15T16:10:15ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512016-05-01193147Can the 3rd Hour Value of 100 g Oral Glucose Tolerance Test Be Ignored in the Diagnosis of Gestational Diabetes Mellitus?Mehmet Metin Altay0Serdinç Özdoğan1Aytaç Tohma2Sertaç Esin3Okyar Erol4Orhan Gelişen5Melih Akkuş6Sinan Karadeniz7Etlik Zübeyde Hanım Obstetrics and Gynecology Teaching and Research Hospital, AnkaraEtlik Zübeyde Hanım Obstetrics and Gynecology Teaching and Research Hospital, AnkaraEtlik Zübeyde Hanım Obstetrics and Gynecology Teaching and Research Hospital, AnkaraEtlik Zübeyde Hanım Obstetrics and Gynecology Teaching and Research Hospital, AnkaraEtlik Zübeyde Hanım Obstetrics and Gynecology Teaching and Research Hospital, AnkaraEtlik Zübeyde Hanım Obstetrics and Gynecology Teaching and Research Hospital, AnkaraEtlik Zübeyde Hanım Obstetrics and Gynecology Teaching and Research Hospital, AnkaraEtlik Zübeyde Hanım Obstetrics and Gynecology Teaching and Research Hospital, AnkaraOBJECTIVE: To investigate whether the 3rd hour value of 100 g oral glucose tolerance test (OGTT) can be ignored when diagnosing gestational diabetes. STUDY DESIGN: During the first 8 months of 2010, 6909 patients between 24 and 28 weeks’ of gestation were screened with 50 g glucose challenge test and 140 mg/dl or higher plasma glucose levels were further evaluated with 100 g OGTT to diagnose gestational diabetes mellitus (GDM). 1195 patients’ test results were acquired for this retrospective study. For the 100 g OGTT fasting plasma glucose cut-off value was 105 mg/dl, 1 hour cut-off value was 190 mg/dl, 2 hour cut-off value was 165 mg/dl and 3 hour cut-off value was 145 mg/dl. Patients with 2 or more values above the cut-off level were diagnosed as GDM. RESULTS: Out of 1195, 124 patients (10.4%) were diagnosed as having GDM. 65 patients (52.4%) had high values of first and second hours; 33 patients (26.6%) had high values of first, second and third hours; 19 patients (15.4%) had second and third hours high values; 7 patients (5.6%) had first and third hours high values of 100 gr OGTT out of those 124 patients. CONCLUSION: 79% of the patients were diagnosed with first and second hour test results but 21% of the patients were diagnosed with blood glucose levels above the third hour cut-off level. Thus, considering the difficulties of 100 gr. OGTT, third hour values is of diagnostic value and cannot be ignored.http://gorm.com.tr/index.php/GORM/article/view/209Gestational diabetes mellitus, Screening, Diagnosis, 100 g oral glucose tolerance test |
| spellingShingle | Mehmet Metin Altay Serdinç Özdoğan Aytaç Tohma Sertaç Esin Okyar Erol Orhan Gelişen Melih Akkuş Sinan Karadeniz Can the 3rd Hour Value of 100 g Oral Glucose Tolerance Test Be Ignored in the Diagnosis of Gestational Diabetes Mellitus? Gynecology Obstetrics & Reproductive Medicine Gestational diabetes mellitus, Screening, Diagnosis, 100 g oral glucose tolerance test |
| title | Can the 3rd Hour Value of 100 g Oral Glucose Tolerance Test Be Ignored in the Diagnosis of Gestational Diabetes Mellitus? |
| title_full | Can the 3rd Hour Value of 100 g Oral Glucose Tolerance Test Be Ignored in the Diagnosis of Gestational Diabetes Mellitus? |
| title_fullStr | Can the 3rd Hour Value of 100 g Oral Glucose Tolerance Test Be Ignored in the Diagnosis of Gestational Diabetes Mellitus? |
| title_full_unstemmed | Can the 3rd Hour Value of 100 g Oral Glucose Tolerance Test Be Ignored in the Diagnosis of Gestational Diabetes Mellitus? |
| title_short | Can the 3rd Hour Value of 100 g Oral Glucose Tolerance Test Be Ignored in the Diagnosis of Gestational Diabetes Mellitus? |
| title_sort | can the 3rd hour value of 100 g oral glucose tolerance test be ignored in the diagnosis of gestational diabetes mellitus |
| topic | Gestational diabetes mellitus, Screening, Diagnosis, 100 g oral glucose tolerance test |
| url | http://gorm.com.tr/index.php/GORM/article/view/209 |
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