Modifying effects of alcohol use and age on the predictive performance of prehospital shock index for functional and survival outcomes in severe trauma patients
This study investigated whether the prehospital shock index (SI) could predict clinical outcomes in trauma patients, with or without pre-injury alcohol consumption, and whether this predictive capacity varied by age. We conducted a retrospective study on severe trauma patients transported to a le...
| প্রধান লেখক: | , , , , , |
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| বিন্যাস: | প্রবন্ধ |
| ভাষা: | English |
| প্রকাশিত: |
MRE Press
2023-09-01
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| মালা: | Journal of Men's Health |
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://oss.jomh.org/files/article/20230928-110/pdf/JOMH2023042902.pdf |
| সংক্ষিপ্ত: | This study investigated whether the prehospital shock index (SI) could predict
clinical outcomes in trauma patients, with or without pre-injury alcohol
consumption, and whether this predictive capacity varied by age. We conducted a
retrospective study on severe trauma patients transported to a level-1 trauma
center by emergency medical services from 2015 to 2021. Our primary exposure was
abnormal SI, defined as an SI ≥0.9, with in-hospital mortality and poor
functional outcomes as study outcomes of interest. Multivariable logistic
regression analysis estimated the effect of SI on clinical outcomes. Our findings
indicated a significant association between abnormal SI and poor functional
outcomes in all trauma patients (adjusted odds ratio: 2.15; 95% confidence
interval: 1.41–3.28), notably pronounced in the older age group (adjusted odds
ratio: 3.56; 95% confidence interval: 1.55–8.30). However, no association was
found with in-hospital mortality. Importantly, among severe trauma patients who
did not consume alcohol, abnormal SI was significantly associated with poor
functional outcomes, irrespective of age, and with increased in-hospital
mortality exclusively in the older age group. Thus, abnormal SI significantly
predicted clinical outcomes in non-alcohol-consuming severe trauma patients, with
the predictive power for in-hospital mortality being specifically significant in
older, non-alcohol-consuming patients. |
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