Expression Patterns, Genomic Conservation and Input Into Developmental Regulation of the GGDEF/EAL/HD-GYP Domain Proteins in Streptomyces

Expression Patterns, Genomic Conservation and Input Into Developmental Regulation of the GGDEF/EAL/HD-GYP Domain Proteins in Streptomyces

To proliferate, antibiotic-producing Streptomyces undergo a complex developmental transition from vegetative growth to the production of aerial hyphae and spores. This morphological switch is controlled by the signaling molecule cyclic bis-(3′,5′) di-guanosine-mono-phosphate (c-di-GMP) that binds to...

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Bibliographic Details
Main Authors: Mahmoud M. Al-Bassam, Julian Haist, Sara Alina Neumann, Sandra Lindenberg, Natalia Tschowri
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Microbiology
Subjects:
c-di-GMP
development
Streptomyces
GGDEF
EAL
HD-GYP
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02524/full

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