Different neurocognitive patterns of conflict control in Tibetans living above and below 4,000 m
Background The existence of a particular threshold of hypoxia severity, beyond which neuropsychological functioning is compromised, is unclear. We investigated the neurocognitive profile related to conflict control in healthy young Tibetans born and living at three different altitudes (2,700 m, 3,70...
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| Format: | Article |
| Language: | English |
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PeerJ Inc.
2019-07-01
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| Series: | PeerJ |
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| Online Access: | https://peerj.com/articles/7269.pdf |
| _version_ | 1827605974369697792 |
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| author | Hailin Ma Buxin Han Yan Wang |
| author_facet | Hailin Ma Buxin Han Yan Wang |
| author_sort | Hailin Ma |
| collection | DOAJ |
| description | Background The existence of a particular threshold of hypoxia severity, beyond which neuropsychological functioning is compromised, is unclear. We investigated the neurocognitive profile related to conflict control in healthy young Tibetans born and living at three different altitudes (2,700 m, 3,700 m, and 4,500 m) in Tibet to investigate the existence of this threshold. Methods Using event-related potentials (ERPs), the conflict control functions of individuals in the three altitude groups were investigated by means of a flanker task, using congruent and incongruent stimuli. The data were analyzed using mixed-model analyses of variance. Results Although effect of altitude was not significant at a behavioral level (p > 0.05), the ERPs showed cognitive conflict modulation. The N2 difference wave (for incongruent minus congruent conditions) was smaller in the 4,500-m group than in the groups living below 4,000 m (p < 0.05). The study’s findings suggest that the influence of high altitude in the conflict monitoring stage becomes significant above 4,000 m. Thus, the altitude threshold for impairment of cognition may be 4,000 m. |
| first_indexed | 2024-03-09T06:31:10Z |
| format | Article |
| id | doaj.art-90f196334b054f14ad60634fe8515573 |
| institution | Directory Open Access Journal |
| issn | 2167-8359 |
| language | English |
| last_indexed | 2024-03-09T06:31:10Z |
| publishDate | 2019-07-01 |
| publisher | PeerJ Inc. |
| record_format | Article |
| series | PeerJ |
| spelling | doaj.art-90f196334b054f14ad60634fe85155732023-12-03T11:05:58ZengPeerJ Inc.PeerJ2167-83592019-07-017e726910.7717/peerj.7269Different neurocognitive patterns of conflict control in Tibetans living above and below 4,000 mHailin Ma0Buxin Han1Yan Wang2Center on Aging Psychology, CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, ChinaCenter on Aging Psychology, CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, ChinaCenter on Aging Psychology, CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, ChinaBackground The existence of a particular threshold of hypoxia severity, beyond which neuropsychological functioning is compromised, is unclear. We investigated the neurocognitive profile related to conflict control in healthy young Tibetans born and living at three different altitudes (2,700 m, 3,700 m, and 4,500 m) in Tibet to investigate the existence of this threshold. Methods Using event-related potentials (ERPs), the conflict control functions of individuals in the three altitude groups were investigated by means of a flanker task, using congruent and incongruent stimuli. The data were analyzed using mixed-model analyses of variance. Results Although effect of altitude was not significant at a behavioral level (p > 0.05), the ERPs showed cognitive conflict modulation. The N2 difference wave (for incongruent minus congruent conditions) was smaller in the 4,500-m group than in the groups living below 4,000 m (p < 0.05). The study’s findings suggest that the influence of high altitude in the conflict monitoring stage becomes significant above 4,000 m. Thus, the altitude threshold for impairment of cognition may be 4,000 m.https://peerj.com/articles/7269.pdfAltitude thresholdConflict controlEvent-related potentials (ERPs)Flanker taskTibetan |
| spellingShingle | Hailin Ma Buxin Han Yan Wang Different neurocognitive patterns of conflict control in Tibetans living above and below 4,000 m PeerJ Altitude threshold Conflict control Event-related potentials (ERPs) Flanker task Tibetan |
| title | Different neurocognitive patterns of conflict control in Tibetans living above and below 4,000 m |
| title_full | Different neurocognitive patterns of conflict control in Tibetans living above and below 4,000 m |
| title_fullStr | Different neurocognitive patterns of conflict control in Tibetans living above and below 4,000 m |
| title_full_unstemmed | Different neurocognitive patterns of conflict control in Tibetans living above and below 4,000 m |
| title_short | Different neurocognitive patterns of conflict control in Tibetans living above and below 4,000 m |
| title_sort | different neurocognitive patterns of conflict control in tibetans living above and below 4 000 m |
| topic | Altitude threshold Conflict control Event-related potentials (ERPs) Flanker task Tibetan |
| url | https://peerj.com/articles/7269.pdf |
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