| Summary: | INTRODUCTION: Urinary retention and nausea and vomiting after spinal anesthesia are common problems. Urinary retention is also a frequent complication after anorectal surgery. Gabapentin and pregabalin have been used successfully in postoperative pain treatment. In this study, we aim to compare the efficacy of gabapentin and pregabalin for postoperative pain, urinary retention, and nausea-vomiting in anorectal surgery patients under spinal anaesthesia. METHODS: The study was carried out randomized and double-blind, placebo-controlled. The 90 patients who underwent elective anorectal surgery were divided into three groups. 300 mg gabapentin in Group G (n=30), 75 mg pregabalin in Group P (n=30), and oral placebo capsül in Group C (n=30) were given orally to the patients 2 hours before surgery. Spinal anesthesia was performed at L4-L5 interspace and a volume of 4 ml of % 0,5 izobarik levobupivacaine and 25 µg fentanil injected through a 25 gauge spinal needle. RESULTS: The number of patients using analgesics within 12 hours was statistically lower in Group G and Group P compered with Group C. There was no statistically significant difference between Group G and Group P. Urinary retention was statistically lower in Group G and Group P than in Group C. There was no statistically significant difference between Group G and Group P in terms of urinary retention. There was no statistically significant difference between groups in terms of nausea and vomiting. DISCUSSION AND CONCLUSION: Preoperatif gabapentin and pregabalin may reduce the postoperative analgesic requirement and incidence of urinary retention in anorectal surgery under spinal anesthesia.
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