Clinical Characteristics, Risk Factors, and Outcomes of Acute Pulmonary Embolism in Asian Population
Background: Acute pulmonary embolism (APE) is a common condition with increasing worldwide incidence. However, the clinical characteristics, risk factors, and clinical outcomes of APE in the Asian population especially in the Thai population are still limited. Therefore, the objective of this study...
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| Format: | Article |
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MDPI AG
2022-11-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/23/6954 |
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| author | Chaiwat Bumroongkit Athavudh Deesomchok Chalerm Liwsrisakun Chaicharn Pothirat Theerakorn Theerakittikul Atikun Limsukon Konlawij Trongtrakul Pattraporn Tajarernmuang Nutchanok Niyatiwatchanchai Arintaya Phrommintikul Tul Chaikitmongkol Juntima Euathrongchit Chartaroon Rimsukcharoenchai Juthamas Inchai Warawut Chaiwong |
| author_facet | Chaiwat Bumroongkit Athavudh Deesomchok Chalerm Liwsrisakun Chaicharn Pothirat Theerakorn Theerakittikul Atikun Limsukon Konlawij Trongtrakul Pattraporn Tajarernmuang Nutchanok Niyatiwatchanchai Arintaya Phrommintikul Tul Chaikitmongkol Juntima Euathrongchit Chartaroon Rimsukcharoenchai Juthamas Inchai Warawut Chaiwong |
| author_sort | Chaiwat Bumroongkit |
| collection | DOAJ |
| description | Background: Acute pulmonary embolism (APE) is a common condition with increasing worldwide incidence. However, the clinical characteristics, risk factors, and clinical outcomes of APE in the Asian population especially in the Thai population are still limited. Therefore, the objective of this study was to identify the clinical characteristics, risk factors, and clinical outcomes of APE in the Asian population. Methods: A cross-sectional study was conducted on patients diagnosed with APE at Chiang Mai University Hospital, Thailand during 2011–2020. Results: During the study period, 696 patients confirmed the diagnosis of APE with a mean age of 57.7 ± 15.7 years and 41.1% males. APE was suspected in 468 of 696 patients (67.2%), while 228 patients (32.8%) had incidental PE. Active malignancy during treatment was found in 388 (55.7%). Dyspnea, cough, and chest pain were the most common presenting symptoms. Respiratory failure was found in 129 patients (18.6%). The thirty-day all-cause mortality rate was 19.1%. PE-related mortality was 5.6%. Most PE-related mortality was high-risk PE. Conclusion: APE was not uncommon in the Asian population. Active cancer, especially lung cancer was the most common risk factors. High-risk and intermediate-high-risk PE were associated with high mortality. Risk stratification and prompt management are warranted to improve outcomes. |
| first_indexed | 2024-03-09T17:43:43Z |
| format | Article |
| id | doaj.art-90f294e79e9445d09d1e1ce182f9ff76 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T17:43:43Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-90f294e79e9445d09d1e1ce182f9ff762023-11-24T11:20:31ZengMDPI AGJournal of Clinical Medicine2077-03832022-11-011123695410.3390/jcm11236954Clinical Characteristics, Risk Factors, and Outcomes of Acute Pulmonary Embolism in Asian PopulationChaiwat Bumroongkit0Athavudh Deesomchok1Chalerm Liwsrisakun2Chaicharn Pothirat3Theerakorn Theerakittikul4Atikun Limsukon5Konlawij Trongtrakul6Pattraporn Tajarernmuang7Nutchanok Niyatiwatchanchai8Arintaya Phrommintikul9Tul Chaikitmongkol10Juntima Euathrongchit11Chartaroon Rimsukcharoenchai12Juthamas Inchai13Warawut Chaiwong14Division of Pulmonary, Critical Care, and Allergy, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDivision of Pulmonary, Critical Care, and Allergy, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDivision of Pulmonary, Critical Care, and Allergy, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDivision of Pulmonary, Critical Care, and Allergy, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDivision of Pulmonary, Critical Care, and Allergy, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDivision of Pulmonary, Critical Care, and Allergy, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDivision of Pulmonary, Critical Care, and Allergy, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDivision of Pulmonary, Critical Care, and Allergy, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDivision of Pulmonary, Critical Care, and Allergy, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDivision of Cardiology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDivision of Cardiology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDivision of Cardiovascular and Thoracic Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDivision of Pulmonary, Critical Care, and Allergy, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDivision of Pulmonary, Critical Care, and Allergy, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandBackground: Acute pulmonary embolism (APE) is a common condition with increasing worldwide incidence. However, the clinical characteristics, risk factors, and clinical outcomes of APE in the Asian population especially in the Thai population are still limited. Therefore, the objective of this study was to identify the clinical characteristics, risk factors, and clinical outcomes of APE in the Asian population. Methods: A cross-sectional study was conducted on patients diagnosed with APE at Chiang Mai University Hospital, Thailand during 2011–2020. Results: During the study period, 696 patients confirmed the diagnosis of APE with a mean age of 57.7 ± 15.7 years and 41.1% males. APE was suspected in 468 of 696 patients (67.2%), while 228 patients (32.8%) had incidental PE. Active malignancy during treatment was found in 388 (55.7%). Dyspnea, cough, and chest pain were the most common presenting symptoms. Respiratory failure was found in 129 patients (18.6%). The thirty-day all-cause mortality rate was 19.1%. PE-related mortality was 5.6%. Most PE-related mortality was high-risk PE. Conclusion: APE was not uncommon in the Asian population. Active cancer, especially lung cancer was the most common risk factors. High-risk and intermediate-high-risk PE were associated with high mortality. Risk stratification and prompt management are warranted to improve outcomes.https://www.mdpi.com/2077-0383/11/23/6954acute pulmonary embolismclinical characteristicsrisk factormortalitythe Asian population |
| spellingShingle | Chaiwat Bumroongkit Athavudh Deesomchok Chalerm Liwsrisakun Chaicharn Pothirat Theerakorn Theerakittikul Atikun Limsukon Konlawij Trongtrakul Pattraporn Tajarernmuang Nutchanok Niyatiwatchanchai Arintaya Phrommintikul Tul Chaikitmongkol Juntima Euathrongchit Chartaroon Rimsukcharoenchai Juthamas Inchai Warawut Chaiwong Clinical Characteristics, Risk Factors, and Outcomes of Acute Pulmonary Embolism in Asian Population Journal of Clinical Medicine acute pulmonary embolism clinical characteristics risk factor mortality the Asian population |
| title | Clinical Characteristics, Risk Factors, and Outcomes of Acute Pulmonary Embolism in Asian Population |
| title_full | Clinical Characteristics, Risk Factors, and Outcomes of Acute Pulmonary Embolism in Asian Population |
| title_fullStr | Clinical Characteristics, Risk Factors, and Outcomes of Acute Pulmonary Embolism in Asian Population |
| title_full_unstemmed | Clinical Characteristics, Risk Factors, and Outcomes of Acute Pulmonary Embolism in Asian Population |
| title_short | Clinical Characteristics, Risk Factors, and Outcomes of Acute Pulmonary Embolism in Asian Population |
| title_sort | clinical characteristics risk factors and outcomes of acute pulmonary embolism in asian population |
| topic | acute pulmonary embolism clinical characteristics risk factor mortality the Asian population |
| url | https://www.mdpi.com/2077-0383/11/23/6954 |
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