End-Point Prediction of Granule Moisture in a ConsiGma<sup>TM</sup>-25 Segmented Fluid Bed Dryer

End-Point Prediction of Granule Moisture in a ConsiGma<sup>TM</sup>-25 Segmented Fluid Bed Dryer

Continuously operated pharmaceutical manufacturing lines often consist of a wet granulation unit operation, followed by a (semi-) continuous dryer. The operating conditions of the dryer are crucial for obtaining a desired final granule moisture. Commercially available dryers lack of a thorough onlin...

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Bibliographic Details
Main Authors: Jakob Rehrl, Stephan Sacher, Martin Horn, Johannes Khinast
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Pharmaceutics
Subjects:
continuous manufacturing
soft sensor
process modeling
continuous drying
Online Access:https://www.mdpi.com/1999-4923/12/5/452

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