Pulmonary Embolism: A Frequent Occurrence in Indian Patients with Symptomatic Lower Limb Venous Thrombosis

Pulmonary embolism (PE) is the most severe complication of deep venous thrombosis (DVT). There have been very few studies to assess the prevalence of PE in Asian patients. The objective of this study was to define the prevalence of PE in patients presenting with suspected lower limb DVT. Methods: Th...

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Main Authors: Rajiv Parakh, Sumit R. Kapadia, Ishita Sen, Sandeep Agarwal, Tarun Grover, Ajay Yadav
Format: Article
Language:English
Published: Elsevier 2006-04-01
Series:Asian Journal of Surgery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1015958409601135
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author Rajiv Parakh
Sumit R. Kapadia
Ishita Sen
Sandeep Agarwal
Tarun Grover
Ajay Yadav
author_facet Rajiv Parakh
Sumit R. Kapadia
Ishita Sen
Sandeep Agarwal
Tarun Grover
Ajay Yadav
author_sort Rajiv Parakh
collection DOAJ
description Pulmonary embolism (PE) is the most severe complication of deep venous thrombosis (DVT). There have been very few studies to assess the prevalence of PE in Asian patients. The objective of this study was to define the prevalence of PE in patients presenting with suspected lower limb DVT. Methods: This was a prospective cohort study at Sir Ganga Ram Hospital, a large multispecialty hospital in New Delhi, India. From January 2001 to July 2004, 1,552 consecutive inpatients and outpatients who presented with clinically suspected lower limb DVT were enrolled in the study. Combined ascending radionuclide venography and lung perfusion scan was performed in all patients. Patients with evidence of pulmonary perfusion defects underwent ventilation lung scan. Results: Radionuclide venography-detectable DVT was noted in 744 patients, of whom 521 (70%) had suprapopliteal DVT. Of patients with DVT, 294 (39.5%) showed a high-probability lung scan and 135 (18.1%) had an intermediate-probability lung scan. Overall, 47% of patients with a high-probability scan had no clinical manifestations suggestive of PE. Conclusion: PE occurs frequently in Indian patients with symptomatic DVT. Increasing awareness will provide us with clearer ideas about the prevalence of venous thromboembolism in Asian countries.
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spelling doaj.art-90f61d5b536d42988683e8715de4da222022-12-21T23:21:47ZengElsevierAsian Journal of Surgery1015-95842006-04-01292869110.1016/S1015-9584(09)60113-5Pulmonary Embolism: A Frequent Occurrence in Indian Patients with Symptomatic Lower Limb Venous ThrombosisRajiv Parakh0Sumit R. Kapadia1Ishita Sen2Sandeep Agarwal3Tarun Grover4Ajay Yadav5Department of Vascular Surgery, Sir Ganga Ram Hospital, New Delhi, IndiaDepartment of Vascular Surgery, Sir Ganga Ram Hospital, New Delhi, IndiaDepartment of Nuclear Medicine, Sir Ganga Ram Hospital, New Delhi, IndiaDepartment of Vascular Surgery, Sir Ganga Ram Hospital, New Delhi, IndiaDepartment of Vascular Surgery, Sir Ganga Ram Hospital, New Delhi, IndiaDepartment of Vascular Surgery, Sir Ganga Ram Hospital, New Delhi, IndiaPulmonary embolism (PE) is the most severe complication of deep venous thrombosis (DVT). There have been very few studies to assess the prevalence of PE in Asian patients. The objective of this study was to define the prevalence of PE in patients presenting with suspected lower limb DVT. Methods: This was a prospective cohort study at Sir Ganga Ram Hospital, a large multispecialty hospital in New Delhi, India. From January 2001 to July 2004, 1,552 consecutive inpatients and outpatients who presented with clinically suspected lower limb DVT were enrolled in the study. Combined ascending radionuclide venography and lung perfusion scan was performed in all patients. Patients with evidence of pulmonary perfusion defects underwent ventilation lung scan. Results: Radionuclide venography-detectable DVT was noted in 744 patients, of whom 521 (70%) had suprapopliteal DVT. Of patients with DVT, 294 (39.5%) showed a high-probability lung scan and 135 (18.1%) had an intermediate-probability lung scan. Overall, 47% of patients with a high-probability scan had no clinical manifestations suggestive of PE. Conclusion: PE occurs frequently in Indian patients with symptomatic DVT. Increasing awareness will provide us with clearer ideas about the prevalence of venous thromboembolism in Asian countries.http://www.sciencedirect.com/science/article/pii/S1015958409601135Asiancomplicationdeep venous thrombosisprevalencepulmonary embolism
spellingShingle Rajiv Parakh
Sumit R. Kapadia
Ishita Sen
Sandeep Agarwal
Tarun Grover
Ajay Yadav
Pulmonary Embolism: A Frequent Occurrence in Indian Patients with Symptomatic Lower Limb Venous Thrombosis
Asian Journal of Surgery
Asian
complication
deep venous thrombosis
prevalence
pulmonary embolism
title Pulmonary Embolism: A Frequent Occurrence in Indian Patients with Symptomatic Lower Limb Venous Thrombosis
title_full Pulmonary Embolism: A Frequent Occurrence in Indian Patients with Symptomatic Lower Limb Venous Thrombosis
title_fullStr Pulmonary Embolism: A Frequent Occurrence in Indian Patients with Symptomatic Lower Limb Venous Thrombosis
title_full_unstemmed Pulmonary Embolism: A Frequent Occurrence in Indian Patients with Symptomatic Lower Limb Venous Thrombosis
title_short Pulmonary Embolism: A Frequent Occurrence in Indian Patients with Symptomatic Lower Limb Venous Thrombosis
title_sort pulmonary embolism a frequent occurrence in indian patients with symptomatic lower limb venous thrombosis
topic Asian
complication
deep venous thrombosis
prevalence
pulmonary embolism
url http://www.sciencedirect.com/science/article/pii/S1015958409601135
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