COMPARATIVE EVALUATION OF SKIN SUTURE IN RATS WITH POLYGLYCAPRONE 25 AND NYLON
ABSTRACT Currently, the market offers a wide variety of suture threads, made of materials with different structural and chemical properties. Among many other characteristics, they vary in origin, absorption or degradation, and structure. From this variety, the clinical doubt arises as to which mater...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Ortopedia e Traumatologia
2023-07-01
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| Series: | Acta Ortopédica Brasileira |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-78522023000600201&lng=en&tlng=en |
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| author | RAFAEL SALEME ALVES LEONARDO YABU TANAKA VICTOR BIGNATTO CARVALHO LETICIA CANDIDO LOPES SOFIA BRANDÃO DOS SANTOS NUHA AHMAD DSOUKI BRUNO FIORELINI PEREIRA MONICA AKEMI SATO |
| author_facet | RAFAEL SALEME ALVES LEONARDO YABU TANAKA VICTOR BIGNATTO CARVALHO LETICIA CANDIDO LOPES SOFIA BRANDÃO DOS SANTOS NUHA AHMAD DSOUKI BRUNO FIORELINI PEREIRA MONICA AKEMI SATO |
| author_sort | RAFAEL SALEME ALVES |
| collection | DOAJ |
| description | ABSTRACT Currently, the market offers a wide variety of suture threads, made of materials with different structural and chemical properties. Among many other characteristics, they vary in origin, absorption or degradation, and structure. From this variety, the clinical doubt arises as to which material provides the patient with the best healing quality. Objective: This study aims to comparatively evaluate two different types of suture threads-Monocryl® (polyglycaprone 25) and Ethilon® (nylon)-regarding their ability to aid in tissue regeneration by a histological and immunohistochemical analysis of the skin of rats sutured with the aforementioned materials. Methods: This basic experimental study used 12 adult Wistar rats, randomly divided into three groups with four animals each and subjected to four longitudinal incisions under anesthesia. Each group corresponded to a postsurgical evaluation date (one, seven, and 14 days). Results: At 14 postoperative days, the studied groups had no histological difference. However, the use of nylon thread showed greater evidence of earlier fibrotic union. Conclusion: This study found no histological difference in healing 14 days after surgery among the techniques and the types of suture threads. Level of Evidence II, Therapeutic Studies. |
| first_indexed | 2024-03-12T20:46:14Z |
| format | Article |
| id | doaj.art-90f62d55a21b438b8fe187d2b10ef730 |
| institution | Directory Open Access Journal |
| issn | 1413-7852 |
| language | English |
| last_indexed | 2024-03-12T20:46:14Z |
| publishDate | 2023-07-01 |
| publisher | Sociedade Brasileira de Ortopedia e Traumatologia |
| record_format | Article |
| series | Acta Ortopédica Brasileira |
| spelling | doaj.art-90f62d55a21b438b8fe187d2b10ef7302023-08-01T07:44:12ZengSociedade Brasileira de Ortopedia e TraumatologiaActa Ortopédica Brasileira1413-78522023-07-0131410.1590/1413-785220233104e266635COMPARATIVE EVALUATION OF SKIN SUTURE IN RATS WITH POLYGLYCAPRONE 25 AND NYLONRAFAEL SALEME ALVEShttps://orcid.org/0000-0002-6208-0574LEONARDO YABU TANAKAhttps://orcid.org/0000-0001-6305-6958VICTOR BIGNATTO CARVALHOhttps://orcid.org/0000-0003-0258-1542LETICIA CANDIDO LOPEShttps://orcid.org/0000-0002-1637-8070SOFIA BRANDÃO DOS SANTOShttps://orcid.org/0000-0002-4961-8499NUHA AHMAD DSOUKIhttps://orcid.org/0000-0001-5882-1600BRUNO FIORELINI PEREIRAhttps://orcid.org/0000-0003-0416-7281MONICA AKEMI SATOhttps://orcid.org/0000-0001-8627-363XABSTRACT Currently, the market offers a wide variety of suture threads, made of materials with different structural and chemical properties. Among many other characteristics, they vary in origin, absorption or degradation, and structure. From this variety, the clinical doubt arises as to which material provides the patient with the best healing quality. Objective: This study aims to comparatively evaluate two different types of suture threads-Monocryl® (polyglycaprone 25) and Ethilon® (nylon)-regarding their ability to aid in tissue regeneration by a histological and immunohistochemical analysis of the skin of rats sutured with the aforementioned materials. Methods: This basic experimental study used 12 adult Wistar rats, randomly divided into three groups with four animals each and subjected to four longitudinal incisions under anesthesia. Each group corresponded to a postsurgical evaluation date (one, seven, and 14 days). Results: At 14 postoperative days, the studied groups had no histological difference. However, the use of nylon thread showed greater evidence of earlier fibrotic union. Conclusion: This study found no histological difference in healing 14 days after surgery among the techniques and the types of suture threads. Level of Evidence II, Therapeutic Studies.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-78522023000600201&lng=en&tlng=enSkinWound HealingSuturesInflammationMetalloproteinasesTissue Inhibitor of Metalloproteinases |
| spellingShingle | RAFAEL SALEME ALVES LEONARDO YABU TANAKA VICTOR BIGNATTO CARVALHO LETICIA CANDIDO LOPES SOFIA BRANDÃO DOS SANTOS NUHA AHMAD DSOUKI BRUNO FIORELINI PEREIRA MONICA AKEMI SATO COMPARATIVE EVALUATION OF SKIN SUTURE IN RATS WITH POLYGLYCAPRONE 25 AND NYLON Acta Ortopédica Brasileira Skin Wound Healing Sutures Inflammation Metalloproteinases Tissue Inhibitor of Metalloproteinases |
| title | COMPARATIVE EVALUATION OF SKIN SUTURE IN RATS WITH POLYGLYCAPRONE 25 AND NYLON |
| title_full | COMPARATIVE EVALUATION OF SKIN SUTURE IN RATS WITH POLYGLYCAPRONE 25 AND NYLON |
| title_fullStr | COMPARATIVE EVALUATION OF SKIN SUTURE IN RATS WITH POLYGLYCAPRONE 25 AND NYLON |
| title_full_unstemmed | COMPARATIVE EVALUATION OF SKIN SUTURE IN RATS WITH POLYGLYCAPRONE 25 AND NYLON |
| title_short | COMPARATIVE EVALUATION OF SKIN SUTURE IN RATS WITH POLYGLYCAPRONE 25 AND NYLON |
| title_sort | comparative evaluation of skin suture in rats with polyglycaprone 25 and nylon |
| topic | Skin Wound Healing Sutures Inflammation Metalloproteinases Tissue Inhibitor of Metalloproteinases |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-78522023000600201&lng=en&tlng=en |
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