Pcdhβ deficiency affects hippocampal CA1 ensemble activity and contextual fear discrimination

Pcdhβ deficiency affects hippocampal CA1 ensemble activity and contextual fear discrimination

Abstract Clustered protocadherins (Pcdhs), a large group of adhesion molecules, are important for axonal projections and dendritic spread, but little is known about how they influence neuronal activity. The Pcdhβ cluster is strongly expressed in the hippocampus, and in vivo Ca2+ imaging in Pcdhβ-def...

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Bibliographic Details
Main Authors: Hirotaka Asai, Noriaki Ohkawa, Yoshito Saitoh, Khaled Ghandour, Emi Murayama, Hirofumi Nishizono, Mina Matsuo, Teruyoshi Hirayama, Ryosuke Kaneko, Shin-ichi Muramatsu, Takeshi Yagi, Kaoru Inokuchi
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Molecular Brain
Subjects:
Hippocampus
CA1
Clustered protocadherin
Pcdhβ
Ca2+ imaging
Ensemble
Online Access:https://doi.org/10.1186/s13041-020-0547-z

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