The Potential Effects of Implementing an Antibiotic Stewardship Program by Integrating It with Medication Therapy Service in a Low-Income Serving Clinic - A Single-Center Experience
Background: Bacterial antimicrobial resistance (AMR) is a leading cause of mortality worldwide. Although AMR is common in low-income communities, there is limited evidence of the effect of antibiotic stewardship programs in low-income communities in the United States. Objectives: Our goal is to a...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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University of Minnesota Libraries Publishing
2022-10-01
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| Series: | INNOVATIONS in Pharmacy |
| Subjects: | |
| Online Access: | https://pubs.lib.umn.edu/index.php/innovations/article/view/4997 |
| _version_ | 1811181183142199296 |
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| author | Arinze Nkemdirim Okere Miquetta L. Trimble Vassiki Sanogo Ukamaka Smith Clyde Brown Sarah G. Buxbaum |
| author_facet | Arinze Nkemdirim Okere Miquetta L. Trimble Vassiki Sanogo Ukamaka Smith Clyde Brown Sarah G. Buxbaum |
| author_sort | Arinze Nkemdirim Okere |
| collection | DOAJ |
| description |
Background: Bacterial antimicrobial resistance (AMR) is a leading cause of mortality worldwide. Although AMR is common in low-income communities, there is limited evidence of the effect of antibiotic stewardship programs in low-income communities in the United States.
Objectives: Our goal is to assess the effects of implementing pharmacist-led ASP by integrating it with medication therapy management service (MTM) in a low-income serving clinic. We evaluated the following 1) antibiotic prescriptions per 1000 patients, 2) the frequency of clinic (office) visits 30-day post-index clinic visits for recurring infections.
Methods: To achieve our goal, we conducted a pre-post, quasi-experimental intervention study using an interrupted time-series analysis to assess the following: 1) antibiotic prescriptions per 1000 patients and the 2) frequency of office visits (including telehealth) within 30-day post-index clinic visits associated with recurrent infection.
Results: Our findings revealed that the long-term effect of our antibiotic stewardship program intervention was associated with 63.69% reduction in antibiotic prescriptions per 1000 patients (change in slope = -0.173, [95% CI: (-0.30, -0.05)], P < 0.007) and a reduction in the frequency of office visits within 30-day post-index clinic visits by 67.27% (change in slope = -2.043, [95% CI: (-3.84, -0.24)], P < 0.028).
Conclusion: Implementing antibiotic stewardship programs is feasible for clinics serving low-income populations. It was associated with a reduction in antibiotic prescriptions and preventable clinic (office) visits within 30 days due to infection recurrence.
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| first_indexed | 2024-04-11T09:15:07Z |
| format | Article |
| id | doaj.art-910352e4a48c4479b308693e8a416a8d |
| institution | Directory Open Access Journal |
| issn | 2155-0417 |
| language | English |
| last_indexed | 2024-04-11T09:15:07Z |
| publishDate | 2022-10-01 |
| publisher | University of Minnesota Libraries Publishing |
| record_format | Article |
| series | INNOVATIONS in Pharmacy |
| spelling | doaj.art-910352e4a48c4479b308693e8a416a8d2022-12-22T04:32:23ZengUniversity of Minnesota Libraries PublishingINNOVATIONS in Pharmacy2155-04172022-10-0113310.24926/iip.v13i3.4997The Potential Effects of Implementing an Antibiotic Stewardship Program by Integrating It with Medication Therapy Service in a Low-Income Serving Clinic - A Single-Center ExperienceArinze Nkemdirim Okere0Miquetta L. Trimble1Vassiki Sanogo2Ukamaka Smith3Clyde Brown4Sarah G. Buxbaum5Florida A&M University, College of PharmacyBond Community Health Center, Tallahassee, FloridaStatistical Consultant and Health EconomicsFlorida A&M University, College of PharmacyFlorida A&M University, College of PharmacyFlorida A&M University, College of Pharmacy Background: Bacterial antimicrobial resistance (AMR) is a leading cause of mortality worldwide. Although AMR is common in low-income communities, there is limited evidence of the effect of antibiotic stewardship programs in low-income communities in the United States. Objectives: Our goal is to assess the effects of implementing pharmacist-led ASP by integrating it with medication therapy management service (MTM) in a low-income serving clinic. We evaluated the following 1) antibiotic prescriptions per 1000 patients, 2) the frequency of clinic (office) visits 30-day post-index clinic visits for recurring infections. Methods: To achieve our goal, we conducted a pre-post, quasi-experimental intervention study using an interrupted time-series analysis to assess the following: 1) antibiotic prescriptions per 1000 patients and the 2) frequency of office visits (including telehealth) within 30-day post-index clinic visits associated with recurrent infection. Results: Our findings revealed that the long-term effect of our antibiotic stewardship program intervention was associated with 63.69% reduction in antibiotic prescriptions per 1000 patients (change in slope = -0.173, [95% CI: (-0.30, -0.05)], P < 0.007) and a reduction in the frequency of office visits within 30-day post-index clinic visits by 67.27% (change in slope = -2.043, [95% CI: (-3.84, -0.24)], P < 0.028). Conclusion: Implementing antibiotic stewardship programs is feasible for clinics serving low-income populations. It was associated with a reduction in antibiotic prescriptions and preventable clinic (office) visits within 30 days due to infection recurrence. https://pubs.lib.umn.edu/index.php/innovations/article/view/4997antibiotics, low-income populations, pharmacist-led Antibiotic Stewardship Programs, medication adherence |
| spellingShingle | Arinze Nkemdirim Okere Miquetta L. Trimble Vassiki Sanogo Ukamaka Smith Clyde Brown Sarah G. Buxbaum The Potential Effects of Implementing an Antibiotic Stewardship Program by Integrating It with Medication Therapy Service in a Low-Income Serving Clinic - A Single-Center Experience INNOVATIONS in Pharmacy antibiotics, low-income populations, pharmacist-led Antibiotic Stewardship Programs, medication adherence |
| title | The Potential Effects of Implementing an Antibiotic Stewardship Program by Integrating It with Medication Therapy Service in a Low-Income Serving Clinic - A Single-Center Experience |
| title_full | The Potential Effects of Implementing an Antibiotic Stewardship Program by Integrating It with Medication Therapy Service in a Low-Income Serving Clinic - A Single-Center Experience |
| title_fullStr | The Potential Effects of Implementing an Antibiotic Stewardship Program by Integrating It with Medication Therapy Service in a Low-Income Serving Clinic - A Single-Center Experience |
| title_full_unstemmed | The Potential Effects of Implementing an Antibiotic Stewardship Program by Integrating It with Medication Therapy Service in a Low-Income Serving Clinic - A Single-Center Experience |
| title_short | The Potential Effects of Implementing an Antibiotic Stewardship Program by Integrating It with Medication Therapy Service in a Low-Income Serving Clinic - A Single-Center Experience |
| title_sort | potential effects of implementing an antibiotic stewardship program by integrating it with medication therapy service in a low income serving clinic a single center experience |
| topic | antibiotics, low-income populations, pharmacist-led Antibiotic Stewardship Programs, medication adherence |
| url | https://pubs.lib.umn.edu/index.php/innovations/article/view/4997 |
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