Evasin‐displaying lactic acid bacteria bind different chemokines and neutralize CXCL8 production in Caco‐2 cells
Summary Chemokines are key signals in the immune system and play an important role as proinflammatory mediators in the pathology of inflammatory bowel disease and colorectal cancer, making them an important target for therapy. Recombinant lactic acid bacteria (LAB) were engineered to bind CC and CXC...
Main Authors: | Katja Škrlec, Anja Pucer Janež, Boris Rogelj, Borut Štrukelj, Aleš Berlec |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2017-11-01
|
Series: | Microbial Biotechnology |
Online Access: | https://doi.org/10.1111/1751-7915.12781 |
Similar Items
-
The N-terminal domain of a tick evasin is critical for chemokine binding and neutralization and confers specific binding activity to other evasins
by: Eaton, J, et al.
Published: (2018) -
Evasins: tick salivary proteins that inhibit mammalian chemokines
by: Bhusal, R, et al.
Published: (2019) -
Chapter One - Using evasins to target the chemokine network in inflammation
by: Bhattacharya, S, et al.
Published: (2019) -
Generating a custom TA-cloning expression plasmid for Lactococcus lactis
by: Aleš Berlec, et al.
Published: (2012-01-01) -
Engineered anti-inflammatory peptides inspired by mapping an evasin-chemokine interaction
by: Darlot, B, et al.
Published: (2020)