Unusual pathological fracture of the clavicle revealing primary hyperparathyroidism: a case report

Abstract Background Primary hyperparathyroidism revealed by a pathological fracture is very uncommon; in the majority of cases the discovery of lytic bone lesions on imaging examinations evokes in the clinician first a neoplastic etiology and a metabolic origin is often omitted. This case report add...

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Main Authors: Yassir Benameur, Hasnae Guerrouj, Imad Ghfir, Nouzha Ben Rais Aouad
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Journal of Medical Case Reports
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13256-017-1509-7
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author Yassir Benameur
Hasnae Guerrouj
Imad Ghfir
Nouzha Ben Rais Aouad
author_facet Yassir Benameur
Hasnae Guerrouj
Imad Ghfir
Nouzha Ben Rais Aouad
author_sort Yassir Benameur
collection DOAJ
description Abstract Background Primary hyperparathyroidism revealed by a pathological fracture is very uncommon; in the majority of cases the discovery of lytic bone lesions on imaging examinations evokes in the clinician first a neoplastic etiology and a metabolic origin is often omitted. This case report adds to the existing literature as it describes an unusual presentation of primary hyperparathyroidism. Case presentation We report a case of a 50-year-old Moroccan man, without any known tumor, who presented a fracture of his left clavicle with multiple osteolytic lesions on computed tomography suggesting bone metastases. However, bone scintigraphy oriented the diagnosis to a metabolic pathology by showing a metabolic bone “super scan” with increased tracer uptake in the left clavicle; parathyroid scintigraphy was able to localize pathological right parathyroid tissue. Conclusions Whenever multiple osteolytic lesions are found in a patient without any known tumor, metabolic bone diseases including hyperparathyroidism should be highly considered.
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spelling doaj.art-910b14ab9d7f4f9c8285c2faa563e14f2022-12-21T19:51:56ZengBMCJournal of Medical Case Reports1752-19472017-12-011111410.1186/s13256-017-1509-7Unusual pathological fracture of the clavicle revealing primary hyperparathyroidism: a case reportYassir Benameur0Hasnae Guerrouj1Imad Ghfir2Nouzha Ben Rais Aouad3Department of Nuclear Medicine, Ibn Sina Hospital, Mohammed V UniversityDepartment of Nuclear Medicine, Ibn Sina Hospital, Mohammed V UniversityDepartment of Nuclear Medicine, Ibn Sina Hospital, Mohammed V UniversityDepartment of Nuclear Medicine, Ibn Sina Hospital, Mohammed V UniversityAbstract Background Primary hyperparathyroidism revealed by a pathological fracture is very uncommon; in the majority of cases the discovery of lytic bone lesions on imaging examinations evokes in the clinician first a neoplastic etiology and a metabolic origin is often omitted. This case report adds to the existing literature as it describes an unusual presentation of primary hyperparathyroidism. Case presentation We report a case of a 50-year-old Moroccan man, without any known tumor, who presented a fracture of his left clavicle with multiple osteolytic lesions on computed tomography suggesting bone metastases. However, bone scintigraphy oriented the diagnosis to a metabolic pathology by showing a metabolic bone “super scan” with increased tracer uptake in the left clavicle; parathyroid scintigraphy was able to localize pathological right parathyroid tissue. Conclusions Whenever multiple osteolytic lesions are found in a patient without any known tumor, metabolic bone diseases including hyperparathyroidism should be highly considered.http://link.springer.com/article/10.1186/s13256-017-1509-7Primary hyperparathyroidismBone scintigraphyParathyroid scintigraphyPathological fractureOsteolytic bone metastases
spellingShingle Yassir Benameur
Hasnae Guerrouj
Imad Ghfir
Nouzha Ben Rais Aouad
Unusual pathological fracture of the clavicle revealing primary hyperparathyroidism: a case report
Journal of Medical Case Reports
Primary hyperparathyroidism
Bone scintigraphy
Parathyroid scintigraphy
Pathological fracture
Osteolytic bone metastases
title Unusual pathological fracture of the clavicle revealing primary hyperparathyroidism: a case report
title_full Unusual pathological fracture of the clavicle revealing primary hyperparathyroidism: a case report
title_fullStr Unusual pathological fracture of the clavicle revealing primary hyperparathyroidism: a case report
title_full_unstemmed Unusual pathological fracture of the clavicle revealing primary hyperparathyroidism: a case report
title_short Unusual pathological fracture of the clavicle revealing primary hyperparathyroidism: a case report
title_sort unusual pathological fracture of the clavicle revealing primary hyperparathyroidism a case report
topic Primary hyperparathyroidism
Bone scintigraphy
Parathyroid scintigraphy
Pathological fracture
Osteolytic bone metastases
url http://link.springer.com/article/10.1186/s13256-017-1509-7
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AT imadghfir unusualpathologicalfractureoftheclaviclerevealingprimaryhyperparathyroidismacasereport
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