Phylogenetic Diversity and Physiological Roles of Plant Monovalent Cation/H+ Antiporters
The processes of plant nutrition, stress tolerance, plant growth, and development are strongly dependent on transport of mineral nutrients across cellular membranes. Plant membrane transporters are key components of these processes. Among various membrane transport proteins, the monovalent cation pr...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-10-01
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| Series: | Frontiers in Plant Science |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fpls.2020.573564/full |
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| author | Stanislav V. Isayenkov Stanislav V. Isayenkov Siarhei A. Dabravolski Ting Pan Sergey Shabala Sergey Shabala |
| author_facet | Stanislav V. Isayenkov Stanislav V. Isayenkov Siarhei A. Dabravolski Ting Pan Sergey Shabala Sergey Shabala |
| author_sort | Stanislav V. Isayenkov |
| collection | DOAJ |
| description | The processes of plant nutrition, stress tolerance, plant growth, and development are strongly dependent on transport of mineral nutrients across cellular membranes. Plant membrane transporters are key components of these processes. Among various membrane transport proteins, the monovalent cation proton antiporter (CPA) superfamily mediates a broad range of physiological and developmental processes such as ion and pH homeostasis, development of reproductive organs, chloroplast operation, and plant adaptation to drought and salt stresses. CPA family includes plasma membrane-bound Na+/H+ exchanger (NhaP) and intracellular Na+/H+ exchanger NHE (NHX), K+ efflux antiporter (KEA), and cation/H+ exchanger (CHX) family proteins. In this review, we have completed the phylogenetic inventory of CPA transporters and undertaken a comprehensive evolutionary analysis of their development. Compared with previous studies, we have significantly extended the range of plant species, including green and red algae and Acrogymnospermae into phylogenetic analysis. Our data suggest that the multiplication and complexation of CPA isoforms during evolution is related to land colonisation by higher plants and associated with an increase of different tissue types and development of reproductive organs. The new data extended the number of clades for all groups of CPAs, including those for NhaP/SOS, NHE/NHX, KEA, and CHX. We also critically evaluate the latest findings on the biological role, physiological functions and regulation of CPA transporters in relation to their structure and phylogenetic position. In addition, the role of CPA members in plant tolerance to various abiotic stresses is summarized, and the future priority directions for CPA studies in plants are discussed. |
| first_indexed | 2024-12-13T08:53:59Z |
| format | Article |
| id | doaj.art-910e7d987ffc4ca58f2c6d3df7e7360b |
| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-12-13T08:53:59Z |
| publishDate | 2020-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-910e7d987ffc4ca58f2c6d3df7e7360b2022-12-21T23:53:19ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2020-10-011110.3389/fpls.2020.573564573564Phylogenetic Diversity and Physiological Roles of Plant Monovalent Cation/H+ AntiportersStanislav V. Isayenkov0Stanislav V. Isayenkov1Siarhei A. Dabravolski2Ting Pan3Sergey Shabala4Sergey Shabala5International Research Centre for Environmental Membrane Biology, Foshan University, Foshan, ChinaDepartment of Plant Food Products and Biofortification, Institute of Food Biotechnology and Genomics NAS of Ukraine, Kyiv, UkraineDepartment of Clinical Diagnostics, Vitebsk State Academy of Veterinary Medicine [UO VGAVM], Vitebsk, BelarusInternational Research Centre for Environmental Membrane Biology, Foshan University, Foshan, ChinaInternational Research Centre for Environmental Membrane Biology, Foshan University, Foshan, ChinaTasmanian Institute of Agriculture, University of Tasmania, Hobart, TAS, AustraliaThe processes of plant nutrition, stress tolerance, plant growth, and development are strongly dependent on transport of mineral nutrients across cellular membranes. Plant membrane transporters are key components of these processes. Among various membrane transport proteins, the monovalent cation proton antiporter (CPA) superfamily mediates a broad range of physiological and developmental processes such as ion and pH homeostasis, development of reproductive organs, chloroplast operation, and plant adaptation to drought and salt stresses. CPA family includes plasma membrane-bound Na+/H+ exchanger (NhaP) and intracellular Na+/H+ exchanger NHE (NHX), K+ efflux antiporter (KEA), and cation/H+ exchanger (CHX) family proteins. In this review, we have completed the phylogenetic inventory of CPA transporters and undertaken a comprehensive evolutionary analysis of their development. Compared with previous studies, we have significantly extended the range of plant species, including green and red algae and Acrogymnospermae into phylogenetic analysis. Our data suggest that the multiplication and complexation of CPA isoforms during evolution is related to land colonisation by higher plants and associated with an increase of different tissue types and development of reproductive organs. The new data extended the number of clades for all groups of CPAs, including those for NhaP/SOS, NHE/NHX, KEA, and CHX. We also critically evaluate the latest findings on the biological role, physiological functions and regulation of CPA transporters in relation to their structure and phylogenetic position. In addition, the role of CPA members in plant tolerance to various abiotic stresses is summarized, and the future priority directions for CPA studies in plants are discussed.https://www.frontiersin.org/article/10.3389/fpls.2020.573564/fullNhaPNa+/H+ exchangerNHEK+-efflux antiporterKEAcation/H+ exchanger |
| spellingShingle | Stanislav V. Isayenkov Stanislav V. Isayenkov Siarhei A. Dabravolski Ting Pan Sergey Shabala Sergey Shabala Phylogenetic Diversity and Physiological Roles of Plant Monovalent Cation/H+ Antiporters Frontiers in Plant Science NhaP Na+/H+ exchanger NHE K+-efflux antiporter KEA cation/H+ exchanger |
| title | Phylogenetic Diversity and Physiological Roles of Plant Monovalent Cation/H+ Antiporters |
| title_full | Phylogenetic Diversity and Physiological Roles of Plant Monovalent Cation/H+ Antiporters |
| title_fullStr | Phylogenetic Diversity and Physiological Roles of Plant Monovalent Cation/H+ Antiporters |
| title_full_unstemmed | Phylogenetic Diversity and Physiological Roles of Plant Monovalent Cation/H+ Antiporters |
| title_short | Phylogenetic Diversity and Physiological Roles of Plant Monovalent Cation/H+ Antiporters |
| title_sort | phylogenetic diversity and physiological roles of plant monovalent cation h antiporters |
| topic | NhaP Na+/H+ exchanger NHE K+-efflux antiporter KEA cation/H+ exchanger |
| url | https://www.frontiersin.org/article/10.3389/fpls.2020.573564/full |
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