Secretory quality control constrains functional selection-associated protein structure innovation
The mismatch in the conserved structure but different expression levels of C-reactive protein (CRP) in distinct species is reconciled by functional selection on hidden activities of unfolded CRPs.
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-03-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-022-03220-3 |
Summary: | The mismatch in the conserved structure but different expression levels of C-reactive protein (CRP) in distinct species is reconciled by functional selection on hidden activities of unfolded CRPs. |
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ISSN: | 2399-3642 |