Reversine suppresses oral squamous cell carcinoma via cell cycle arrest and concomitantly apoptosis and autophagy

Reversine suppresses oral squamous cell carcinoma via cell cycle arrest and concomitantly apoptosis and autophagy

<p>Abstract</p> <p>Background</p> <p>The effective therapies for oral cancer patients of stage III and IV are generally surgical excision and radiation combined with adjuvant chemotherapy using 5-Fu and Cisplatin. However, the five-year survival rate is still less than...

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Bibliographic Details
Main Authors: Lee Ying-Ray, Wu Wei-Ching, Ji Wen-Tsai, Chen Jeff, Cheng Ya-Ping, Chiang Ming-Ko, Chen Hau-Ren
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Journal of Biomedical Science
Subjects:
Reversine
cell cycle arrest
apoptosis
autophagy
oral squamous cell carcinoma (OSCC)
Online Access:http://www.jbiomedsci.com/content/19/1/9

Internet

http://www.jbiomedsci.com/content/19/1/9

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