Progress in studies of gene therapy for Huntington's disease

Progress in studies of gene therapy for Huntington's disease

Huntington's disease (HD) is a kind of inherited neurodegenerative disorder characterized by movement problems, cognitive decline and psychiatry disturbance. HD is caused by mutation in gene IT ⁃15 involving the expansion of a trinucleotide (CAG) repeat encoding glutamine, which leads to abnorm...

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Bibliographic Details
Main Authors: Fan⁃ying JIN, Bao⁃rong ZHANG
Format: Article
Language:English
Published: Tianjin Huanhu Hospital 2012-06-01
Series:Chinese Journal of Contemporary Neurology and Neurosurgery
Subjects:
Huntington disease
Gene therapy
RNA interference
Review
Online Access:http://www.cjcnn.org/index.php/cjcnn/article/view/327

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