Citrinin-Induced Hepatotoxicity in Mice Is Regulated by the Ca<sup>2+</sup>/Endoplasmic Reticulum Stress Signaling Pathway

Citrinin-Induced Hepatotoxicity in Mice Is Regulated by the Ca<sup>2+</sup>/Endoplasmic Reticulum Stress Signaling Pathway

Citrinin (CTN) is a mycotoxin found in crops and agricultural products and poses a serious threat to human and animal health. The aim of this study is to investigate the hepatotoxicity of CTN in mice and analyze its mechanisms from Ca<sup>2+</sup>-dependent endoplasmic reticulum (ER) str...

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Bibliographic Details
Main Authors: Dongyi Wu, Chenglin Yang, Mengran Yang, You Wu, Yan Mao, Xinyan Zhou, Ji Wang, Zhihang Yuan, Jing Wu
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Toxins
Subjects:
citrinin
endoplasmic reticulum stress
oxidative stress
apoptosis
hepatotoxicity
4-phenylbutyric acid
Online Access:https://www.mdpi.com/2072-6651/14/4/259

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