Coronary artery calcifications on breast cancer radiotherapy planning CT scans and cardiovascular risk: What do patients want to know?
Background: Coronary artery calcifications (CAC) is a strong predictor of cardiovascular disease (CVD), which can be automatically quantified on routine breast radiotherapy planning computed tomography (CT) scans. Around 8% of patients have (very) high CAC scores and corresponding increased risks of...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-12-01
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| Series: | International Journal of Cardiology. Cardiovascular Risk and Prevention |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772487521000155 |
| _version_ | 1798025230553186304 |
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| author | Roxanne Gal Madelijn L. Gregorowitsch Marleen J. Emaus Erwin LA. Blezer Femke van der Leij Sanne GM. van Velzen Julia J. van Tol-Geerdink Ivana Išgum Helena M. Verkooijen |
| author_facet | Roxanne Gal Madelijn L. Gregorowitsch Marleen J. Emaus Erwin LA. Blezer Femke van der Leij Sanne GM. van Velzen Julia J. van Tol-Geerdink Ivana Išgum Helena M. Verkooijen |
| author_sort | Roxanne Gal |
| collection | DOAJ |
| description | Background: Coronary artery calcifications (CAC) is a strong predictor of cardiovascular disease (CVD), which can be automatically quantified on routine breast radiotherapy planning computed tomography (CT) scans. Around 8% of patients have (very) high CAC scores and corresponding increased risks of CVD. Aim: This study explores whether, how, and under what conditions women with breast cancer want to be informed about their CAC-based CVD risk. Methods: A cross-sectional survey study was conducted in a random sample of UMBRELLA, a prospective breast cancer cohort. Participants (n = 79) filled out a questionnaire about their knowledge on the CVD risk following breast cancer, their interest in being informed about their CVD risk based on CAC score, and preferences on how they would want to receive this information. Results: Most participants (66%) were not aware that the presence of CAC indicates an increased CVD risk. Participants indicated that they were not or only slightly aware of the risk of treatment-induced cardiotoxicity (48%), and that the risk of cardiotoxicity was higher in patients with pre-existing CVD risk factors (82%). The vast majority (90%) indicated that they want to be informed about in increased CAC-based CVD risk. Conclusions: The majority of patients with breast cancer wants to be informed about their CAC-based CVD risk. With the majority of patients with breast cancer undergoing radiotherapy, and with low cost and automated options for accurate CAC measurement in planning CT scans, it is important to develop strategies to manage patients with an increased CAC-based risk of CVD. |
| first_indexed | 2024-04-11T18:15:25Z |
| format | Article |
| id | doaj.art-911e3f032d104a318779f9b51d75e4d6 |
| institution | Directory Open Access Journal |
| issn | 2772-4875 |
| language | English |
| last_indexed | 2024-04-11T18:15:25Z |
| publishDate | 2021-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Cardiology. Cardiovascular Risk and Prevention |
| spelling | doaj.art-911e3f032d104a318779f9b51d75e4d62022-12-22T04:09:56ZengElsevierInternational Journal of Cardiology. Cardiovascular Risk and Prevention2772-48752021-12-0111200113Coronary artery calcifications on breast cancer radiotherapy planning CT scans and cardiovascular risk: What do patients want to know?Roxanne Gal0Madelijn L. Gregorowitsch1Marleen J. Emaus2Erwin LA. Blezer3Femke van der Leij4Sanne GM. van Velzen5Julia J. van Tol-Geerdink6Ivana Išgum7Helena M. Verkooijen8Division of Imaging and Oncology, University Medical Center Utrecht, Utrecht University, the Netherlands; Corresponding author. Division of Imaging and Oncology, University Medical Center (UMC) Utrecht, Internal no. E.01.132, PO Box 85500, 3508, GA, Utrecht, the Netherlands.Division of Imaging and Oncology, University Medical Center Utrecht, Utrecht University, the NetherlandsDivision of Imaging and Oncology, University Medical Center Utrecht, Utrecht University, the NetherlandsDivision of Imaging and Oncology, University Medical Center Utrecht, Utrecht University, the NetherlandsDepartment of Radiation Oncology, University Medical Center Utrecht, the NetherlandsImage Sciences Institute, University Medical Center Utrecht, Utrecht University, the Netherlands; Department of Biomedical Engineering and Physics, Amsterdam University Medical Centers-location AMC, University of Amsterdam, the NetherlandsDepartment of Radiation Oncology, Radboudumc, the NetherlandsImage Sciences Institute, University Medical Center Utrecht, Utrecht University, the Netherlands; Department of Biomedical Engineering and Physics, Amsterdam University Medical Centers-location AMC, University of Amsterdam, the Netherlands; Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centers – Location AMC, University of Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centers – Location AMC, University of Amsterdam, the NetherlandsDivision of Imaging and Oncology, University Medical Center Utrecht, Utrecht University, the NetherlandsBackground: Coronary artery calcifications (CAC) is a strong predictor of cardiovascular disease (CVD), which can be automatically quantified on routine breast radiotherapy planning computed tomography (CT) scans. Around 8% of patients have (very) high CAC scores and corresponding increased risks of CVD. Aim: This study explores whether, how, and under what conditions women with breast cancer want to be informed about their CAC-based CVD risk. Methods: A cross-sectional survey study was conducted in a random sample of UMBRELLA, a prospective breast cancer cohort. Participants (n = 79) filled out a questionnaire about their knowledge on the CVD risk following breast cancer, their interest in being informed about their CVD risk based on CAC score, and preferences on how they would want to receive this information. Results: Most participants (66%) were not aware that the presence of CAC indicates an increased CVD risk. Participants indicated that they were not or only slightly aware of the risk of treatment-induced cardiotoxicity (48%), and that the risk of cardiotoxicity was higher in patients with pre-existing CVD risk factors (82%). The vast majority (90%) indicated that they want to be informed about in increased CAC-based CVD risk. Conclusions: The majority of patients with breast cancer wants to be informed about their CAC-based CVD risk. With the majority of patients with breast cancer undergoing radiotherapy, and with low cost and automated options for accurate CAC measurement in planning CT scans, it is important to develop strategies to manage patients with an increased CAC-based risk of CVD.http://www.sciencedirect.com/science/article/pii/S2772487521000155Breast cancerCACCardiovascular diseaseCoronary artery calcificationsPatient preferences |
| spellingShingle | Roxanne Gal Madelijn L. Gregorowitsch Marleen J. Emaus Erwin LA. Blezer Femke van der Leij Sanne GM. van Velzen Julia J. van Tol-Geerdink Ivana Išgum Helena M. Verkooijen Coronary artery calcifications on breast cancer radiotherapy planning CT scans and cardiovascular risk: What do patients want to know? International Journal of Cardiology. Cardiovascular Risk and Prevention Breast cancer CAC Cardiovascular disease Coronary artery calcifications Patient preferences |
| title | Coronary artery calcifications on breast cancer radiotherapy planning CT scans and cardiovascular risk: What do patients want to know? |
| title_full | Coronary artery calcifications on breast cancer radiotherapy planning CT scans and cardiovascular risk: What do patients want to know? |
| title_fullStr | Coronary artery calcifications on breast cancer radiotherapy planning CT scans and cardiovascular risk: What do patients want to know? |
| title_full_unstemmed | Coronary artery calcifications on breast cancer radiotherapy planning CT scans and cardiovascular risk: What do patients want to know? |
| title_short | Coronary artery calcifications on breast cancer radiotherapy planning CT scans and cardiovascular risk: What do patients want to know? |
| title_sort | coronary artery calcifications on breast cancer radiotherapy planning ct scans and cardiovascular risk what do patients want to know |
| topic | Breast cancer CAC Cardiovascular disease Coronary artery calcifications Patient preferences |
| url | http://www.sciencedirect.com/science/article/pii/S2772487521000155 |
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